成果/Result
- A Review of the Preparation, Analysis and Biological Functions of Chitooligosaccharide被引量：100收藏
- 作者：Liang, Shuang Sun, Yaxuan Dai, Xueling
- 机构：Beijing Union Univ;Beijing Union Univ
- 来源：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018
- 关键词：chitin chitosan chitooligosaccharide (COS) COS preparation COS analysis COS biological activity
- Neuroprotective effect of liquiritin against focal cerebral ischemia/reperfusion in mice via its antioxidant and antiapoptosis properties被引量：86收藏
- 作者：Sun, Ya-Xuan Tang, Yue Wu, Ai-Li Liu, Ting Dai, Xue-Ling Zheng, Qiu-Sheng Wang, Zhi-Bin
- 机构：Beijing Inst Drug Control;Beijing Union Univ;Chinese Acad Sci;Chinese Acad Med Sci;Chinese Acad Med Sci
- 来源：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 2010
- 关键词：liquiritin mice focal cerebral ischemia reperfusion antioxidant anti-apoptosis
- Chitosan oligosaccharides alleviate cognitive deficits in an amyloid-beta(1-42)-induced rat model of Alzheimer's disease被引量：80收藏
- 作者：Jia, Shiliang Lu, Zheng Gao, Zhaolan An, Jun Wu, Xueling Li, Xiaoxiao Dai, Xueling Zheng, Qiusheng Sun, Yaxuan
- 机构：Beijing Union Univ;Binzhou Med Univ
- 来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2016
- 关键词：Alzheimer's disease Amyloid-beta(1-42) Chitosan oligosaccharides Oxidative stress Neuroinflammation
- Chitosan Oligosaccharides Inhibit/Disaggregate Fibrils and Attenuate Amyloid beta-Mediated Neurotoxicity被引量：41收藏
- 作者：Dai, Xueling Hou, Wanqi Sun, Yaxuan Gao, Zhaolan Zhu, Shigong Jiang, Zhaofeng
- 机构：Beijing Union Univ;Capital Normal Univ;Peking Univ
- 来源：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2015
- 关键词：Alzheimer's disease amyloid- peptide chitosan oligosaccharides aggregation neurotoxicity
- Chitosan oligosaccharides protect rat primary hippocampal neurons from oligomeric beta-amyloid 1-42-induced neurotoxicity被引量：39收藏
- 作者：Dai, Xueling Chang, Ping Zhu, Qingzhu Liu, Wenjuan Sun, Yaxuan Zhu, Shigong Jiang, Zhaofeng
- 机构：Beijing Union Univ;Peking Univ;Beijing Union Univ
- 来源：NEUROSCIENCE LETTERS 2013
- 关键词：Alzheimer's disease beta-Amyloid peptide Chitosan oligosaccharides Neurotoxicity
- Copper Enhances Amyloid-beta Peptide Neurotoxicity and non beta-Aggregation: A Series of Experiments Conducted upon Copper-Bound and Copper-Free Amyloid-beta Peptide被引量：38收藏
- 作者：Dai, Xueling Sun, Yaxuan Gao, Zhaolan Jiang, Zhaofeng
- 机构：Beijing Union Univ;Beijing Union Univ
- 来源：JOURNAL OF MOLECULAR NEUROSCIENCE 2010
- 关键词：Alzheimer's disease Amyloid-beta peptide beta aggregation Neurotoxicity
- Acetylsalicylic acid (ASA) induced fusarium rot resistance and suppressed neosolaniol production by elevation of ROS metabolism in muskmelon fruit被引量：33收藏
- 作者：Xue Huali Sun Yaxuan Li Lan Bi Yang Hussain Raza Zhang Rui Long Haitao Nan Mina Pu Lumei
- 机构：Beijing Union Univ;Gansu Agr Univ;Gansu Agr Univ;Univ Cent Punjab
- 来源：SCIENTIA HORTICULTURAE 2020
- 关键词：Muskmelon Acetylsalicylic acid Trichothecenes ROS metabolism Fusarium rot
- Neuroprotective effects of liquiritin on cognitive deficits induced by soluble amyloid-beta(1-42) oligomers injected into the hippocampus被引量：31收藏
- 作者：Jia, Shi-Liang Wu, Xue-Ling Li, Xiao-Xiao Dai, Xue-Ling Gao, Zhao-Lan Lu, Zheng Zheng, Qiu-Sheng Sun, Ya-Xuan
- 机构：Beijing Union Univ;Binzhou Med Univ
- 来源：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 2016
- 关键词：Liquiritin alzheimer's disease amyloid-beta(1-42) oxidative stress apoptosis
- Treatment with lutein provides neuroprotection in mice subjected to transient cerebral ischemia被引量：27收藏
- 作者：Sun, Ya-Xuan Liu, Ting Dai, Xue-Ling Zheng, Qiu-Sheng Hui, Bo-Di Jiang, Zhao-Feng
- 机构：Beijing Union Univ;Shihezi Univ
- 来源：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 2014
- 关键词：oxidative stress lutein neuroprotection antioxidant transient cerebral ischemia
- Rapid Identification of Tanshinone IIA Metabolites in an Amyloid-beta(1-42) Induced Alzherimer's Disease Rat Model using UHPLC-Q-Exactive Qrbitrap Mass Spectrometry被引量：12收藏
- 作者：Liang, Shuang Wang, Zijian Yuan, Jiaqi Zhang, Jing Dai, Xueling Qin, Fei Zhang, Jiayu Sun, Yaxuan
- 机构：Beijing Union Univ;Beijing Univ Chinese Med;Beijing Union Univ;Binzhou Med Univ
- 来源：MOLECULES 2019
- 关键词：Tanshinone IIA Alzheimer's disease UHPLC-Q-Exactive Qrbitrap mass spectrometry metabolic pathway hippocampus rat model Morris water maze test passive avoidance test
- Screening of Siderophore-Producing Bacteria and Their Effects on Promoting the Growth of Plants被引量：12收藏
- 作者：Sun, Yaxuan Wu, Juanli Shang, Xiaoya Xue, Lingui Ji, Guangyang Chang, Sijing Niu, Junbo Emaneghemi, Brown
- 机构：Beijing Union Univ;Lanzhou Jiaotong Univ;Lanzhou Jiaotong Univ
- 来源：CURRENT MICROBIOLOGY 2022
- A beta-40 Y10F Increases beta fibrils Formation but Attenuates the Neurotoxicity of Amyloid-beta Peptide被引量：12收藏
- 作者：Dai, Xueling Chang, Ping Liu, Wenjuan Xu, Ke Sun, Yaxuan Zhu, Shigong Jiang, Zhaofeng
- 机构：Peking Univ;Beijing Union Univ;Capital Normal Univ
- 来源：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2012
- 关键词：Alzheimer's disease amyloid-beta peptide beta fibrils neurotoxicity
- The inhibitory effect of chitosan oligosaccharides on beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) in HEK293 APPswe cells被引量：11收藏
- 作者：Dai, Xueling Chang, Ping Li, Xiaoxiao Gao, Zhaolan Sun, Yaxuan
- 机构：Beijing Union Univ;Beijing Union Univ
- 来源：NEUROSCIENCE LETTERS 2018
- 关键词：Alzheimer's disease beta-Amyloid peptide Chitosan oligosaccharides beta-Site amyloid precursor protein cleaving enzyme 1 (BACE1)
- Structural and Hirshfeld Surface Analyses of a Novel Hetero-Tetranuclear Cu-II-Na-I Bis(Salamo)-Based Coordination Compound被引量：10收藏
- 作者：Sun, Ya-Xuan Liu, Ling-Zhi Wang, Fei Shang, Xiao-Ya Chen, Le Dong, Wen-Kui
- 机构：Beijing Union Univ;Lanzhou Jiaotong Univ
- 来源：CRYSTALS 2018
- 关键词：bis(Salamo)-type ligand hetero-tetranuclear Cu-II-Na-I coordination compound crystal structure hirshfeld surface analysis
- Acetylsalicylic acid treatment reduce Fusarium rot development and neosolaniol accumulation in muskmelon fruit被引量：10收藏
- 作者：Xue Huali Bi Yang Sun Yaxuan Raza, Hussain Wang Hujun Zhang Shan Zhang Rui Long Haitao Nan Mina Cheng Xiaoyan Calderoon-Urrea, Alejandro
- 机构：Gansu Agr Univ;Gansu Agr Univ;Beijing Union Univ;Univ Cent Punjab;Gansu Agr Univ
- 来源：FOOD CHEMISTRY 2019
- 关键词：Muskmelon Fusarium sulphureum Trichothecenes ASA Fusarium rot
- Inhibitory effects of curcumin on H2O2-induced cell damage and APP expression and processing in SH-SY5Y cells transfected with APP gene with Swedish mutation被引量：8收藏
- 作者：Song, Xi-Jun Zhou, He-Yan Sun, Ya-Xuan Huang, Han-Chang
- 机构：Beijing Union Univ
- 来源：MOLECULAR BIOLOGY REPORTS 2020
- 关键词：Alzheimer's disease Amyloid-beta protein precursor (APP) Amyloid-beta peptide Cell damage Hydrogen peroxide (H2O2) Curcumin Mitochondrial stress
- Rapid screening and characterization of caffeic acid metabolites in rats by UHPLC-Q-TOF mass spectrometry被引量：7收藏
- 作者：Yuan, Jiaqi Wang, Yunting Mi, Shengquan Zhang, Jiayu Sun, Yaxuan
- 机构：Beijing Union Univ;Binzhou Med Univ
- 来源：TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH 2021
- 关键词：Caffeic acid UHPLC-Q-TOF-MS/MS Metabolic profiling
- Rapid Identification of 3,6 '-Disinapoyl Sucrose Metabolites in Alzheimer's Disease Model Mice Using UHPLC-Orbitrap Mass Spectrometry被引量：6收藏
- 作者：Yuan, Jiaqi Wang, Han Wang, Yunting Wang, Zijian Huo, Qing Dai, Xueling Zhang, Jiayu Sun, Yaxuan
- 机构：Beijing Union Univ;Beijing Univ Chinese Med;Binzhou Med Univ
- 来源：MOLECULES 2022
- 关键词：Alzheimer's disease 3,6 '-disinapoyl sucrose UHPLC-Orbitrap mass spectrometry metabolites metabolic pathway
- Protective effects of fisetin in an A beta(1-42)-induced rat model of Alzheimer's disease被引量：2收藏
- 作者：Wang, Yunting Wu, Xueling Ren, Wujiang Liu, Yanxia Dai, Xueling Wang, Shuo Huo, Qing Sun, Yaxuan
- 机构：Beijing Union Univ;Nankai Univ
- 来源：FOLIA NEUROPATHOLOGICA 2023
- 关键词：Alzheimer's disease A beta(1-42) fisetin protective effects mechanism
- 3,6'-Disinapoylsucrose alleviates the amyloid precursor protein and lipopolysaccharide induced cognitive dysfunction through upregulation of the TrkB/BDNF pathway被引量：2收藏
- 作者：Wang, Yun-Ting Wang, Han Ren, Wu-Jiang Dai, Xue-Ling Huo, Qing Wang, Shuo Sun, Ya-Xuan
- 机构：Beijing Union Univ;Beijing Union Univ;Nankai Univ
- 来源：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 0
- 关键词：Alzheimer's disease BDNF TrkB LPS neuroinflammation
- Study on the speciation of arsenic in the genuine medicinal material honeysuckle被引量：1收藏
- 作者：Peng, Congnan Zhou, Juntong Sun, Yaxuan Yin, Hang Chen, Yuxin Yao, Li Qi, Kailin Huo, Qing Xie, Fei
- 机构：Beijing Union Univ
- 来源：OPEN CHEMISTRY 2021
- 关键词：honeysuckle speciation of arsenic HPLC-ICP-MS
- Study on arsenic speciation and redistribution mechanism in Lonicera japonica plants via synchrotron techniques被引量：1收藏
- 作者：Qiao, Jiaqi Zhou, Juntong Peng, Congnan Yuan, Xin Yao, Li Fan, Yilin Qi, Kailin Chen, Dongliang Guo, Zhiying Gan, Xiaolong Sun, Yaxuan Dai, Xueling Wu, Guohao Huo, Qing
- 机构：Beijing Union Univ;Chinese Acad Sci;Sci Res Inst Beijing Tongrentang Co Ltd;Beijing Union Univ
- 来源：OPEN CHEMISTRY 2023
- 关键词：arsenic speciation Lonicera japonica dimethyl arsenate acid synchrotron X-ray fluorescence spectroscopy correlation analysis
- The immunometabolic reprogramming of microglia in Alzheimer's disease被引量：1收藏
- 作者：Chen, Hongli Guo, Zichen Sun, Yaxuan Dai, Xueling
- 机构：Beijing Union Univ
- 来源：NEUROCHEMISTRY INTERNATIONAL 2023
- 关键词：Microglia Immunometabolism Reprogramming Neuroinflammation Alzheimer's disease
- Neuroprotective Activity of Water Soluble Extract from Chorispora bungeana against Focal Cerebral Ischemic/Reperfusion Injury in Mice被引量：0收藏
- 作者：Sun, Ya-Xuan Liu, Ting Dai, Xue-Ling Li, Ya-Bo Li, Yu-Yao Zhang, Hua An, Li-Zhe
- 机构：Beijing Union Univ;Chinese Acad Sci;Shihezi Univ;Lanzhou Univ
- 来源：JOURNAL OF CHEMISTRY 2014
- Effects of Tanshinone IIA on Cognitive Impairment in Alzheimer's Disease Rats Via Oxidative Stress, Inflammatory Responses and Apoptosis被引量：0收藏
- 作者：Ren, Wujiang Li, Xiaoxiao Wang, Tingqiao Liu, Yanxia Dai, Xueling Huo, Qing Wang, Shuo Zheng, Qiusheng Sun, Yaxuan
- 机构：Beijing Union Univ;Nankai Univ;Binzhou Med Univ
- 来源：PHARMACOGNOSY MAGAZINE 2024
- 关键词：Tanshinone IIA cognitive impairment oxidative stress inflammation Alzheimer's disease
- Research Progress in the Analysis of Chemical Forms of Mercury in Traditional Chinese Medicine被引量：0收藏
- 作者：Peng, Congnan Kang, Liping Yuan, Xin Qiao, Jiaqi Fan, Yilin Yao, Li Qi, Kailin Sun, Yaxuan Dai, Xueling Zhang, Yuan Huo, Qing
- 机构：Beijing Union Univ;China Acad Chinese Med Sci
- 来源：PROCESSES 2023
- 关键词：analysis of chemical state mercury research progress traditional Chinese medicine
- Effects of Varied Forms of Arsenic Stress on Seedling Growth and Arsenic Distribution in Honeysuckle Plants被引量：0收藏
- 作者：Yuan, Xin Zhou, Juntong Peng, Congnan Qiao, Jiaqi Xia, Shengqi Fan, Yilin Yao, Li Qi, Kailin Chen, Dongliang Guo, Zhiying Gan, Xiaolong Sun, Yaxuan Dai, Xueling Lv, Liangyu Ji, Yizhi Huo, Qing
- 机构：Beijing Union Univ;Chinese Acad Sci;Donghua Univ
- 来源：PROCESSES 2023
- 关键词：arsenic stress honeysuckle micro X-ray fluorescence physiological indicators
- The Lactobacillus plantarum P-8 Probiotic Microcapsule Prevents DSS-Induced Colitis through Improving Intestinal Integrity and Reducing Colonic Inflammation in Mice被引量：0收藏
- 作者：Wang, Han Sun, Yaxuan Ma, Xuan Yang, Tianyu Wang, Feng
- 机构：Beijing Union Univ
- 来源：NUTRIENTS 2024
- 关键词：probiotic microcapsules colitis intestinal mucosal barriers inflammation NLRP3
- 3,6′-Disinapoyl sucrose alleviates cognitive deficits in APP/PS1 transgenic mice被引量：0收藏
- 作者：Yuan, Jiaqi He, Mengjie Dai, Xueling Huo, Qing Chang, Ping Zhang, Jing Wang, Shuo Sun, Yaxuan
- 机构：Beijing Union Univ;Nankai Univ
- 来源：JOURNAL OF NEUROPHYSIOLOGY 2023
- 关键词：Alzheimer's disease apoptosis CREB/BDNF signal pathway 3,6'-disinapoyl sucrose Morris water maze
