文献类型：期刊文献

英文题名：A Review of the Preparation, Analysis and Biological Functions of Chitooligosaccharide

作者：Liang, Shuang[1];Sun, Yaxuan[2];Dai, Xueling[1]

第一作者：Liang, Shuang

通讯作者：Dai, XL[1]

机构：[1]Beijing Union Univ, Beijing Key Lab Bioact Subst & Funct Foods, Beijing 100191, Peoples R China;[2]Beijing Union Univ, Dept Food Sci, Coll Biochem Engn, Beijing 100023, Peoples R China

第一机构：北京联合大学应用文理学院|北京联合大学生物化学工程学院

通讯机构：[1]corresponding author), Beijing Union Univ, Beijing Key Lab Bioact Subst & Funct Foods, Beijing 100191, Peoples R China.|[1141726]北京联合大学生物化学工程学院;[11417]北京联合大学;[114172]北京联合大学应用文理学院;

年份：2018

卷号：19

期号：8

外文期刊名：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

收录：;Scopus(收录号：2-s2.0-85052075184);WOS:【SCI-EXPANDED(收录号:WOS:000442869800049)】；

基金：This research was supported by grants from the Beijing Natural Science Foundation (6164030), Scientific Research Common Program of Beijing Municipal Commission of Education (SQKM201511417013), Beijing Municipal Outstanding Talent Training Funding (2015000020124G049), Premium Funding Project for Academic Human Resources Development in Beijing Union University (BPHR2018DZ03), Beijing Key Laboratory of Bioactive Substances and Functional Foods Research Project, and Graduate Funding Project in Beijing Union University.

语种：英文

外文关键词：chitin; chitosan; chitooligosaccharide (COS); COS preparation; COS analysis; COS biological activity

摘要：Chitooligosaccharide (COS), which is acknowledged for possessing multiple functions, is a kind of low-molecular-weight polymer prepared by degrading chitosan via enzymatic, chemical methods, etc. COS has comprehensive applications in various fields including food, agriculture, pharmacy, clinical therapy, and environmental industries. Besides having excellent properties such as biodegradability, biocompatibility, adsorptive abilities and non-toxicity like chitin and chitosan, COS has better solubility. In addition, COS has strong biological functions including anti-inflammatory, antitumor, immunomodulatory, neuroprotective effects, etc. The present paper has summarized the preparation methods, analytical techniques and biological functions to provide an overall understanding of the application of COS.