文献类型：期刊文献

中文题名：均匀设计优选微波辅助萃取白芷香豆素类成分

英文题名：Microwave-assisted extraction process of coumarins in Angelica dahurica with Uniform design

作者：刘红梅[1]

第一作者：刘红梅

机构：[1]北京联合大学生物化学工程学院

第一机构：北京联合大学生物化学工程学院

年份：2004

卷号：19

期号：3

起止页码：193-195

中文期刊名：华西药学杂志

外文期刊名：West China Journal of Pharmaceutical Sciences

收录：CSTPCD;;CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：微波辅助萃取;白芷香豆素类;欧前胡素;萃取方法

外文关键词：Microwave-assisted extraction;Angelica dahurica;Imperatorin;Uniform design

摘要：目的　以欧前胡素含量为试验指标 ,优化微波萃取白芷有效成分的提取工艺。方法　通过均匀设计方法 ,采用连续微波辐射方法。结果　微波功率、微波辐射时间、溶剂用量、溶剂浓度、浸泡时间、药材粉碎度等参数对白芷有效成分的提取具有交互作用 ,优选出的最佳萃取工艺为 :微波功率 4 5 0W ,辐射时间 10min ,浸泡时间 30min ,固液比为 1∶4 ,乙醇浓度为 95 % ,粉碎度为 4 0目。结论　建立的数学模型和优化结果合理 ,微波萃取白芷有效成分是可行的。
OBJECTIVE To optimize the microwave-assisted extraction process for coumarins in Angelica dahurica as guided by the contents of imperatorin.METHODS The continuous microwave radiation process was adopted.The optimized extraction process was established using the uniform design.RESULTS Some parameters such as the microwave power,radiation time,solvent consumption,solvent concentration,dipping time and pulverized degree had interactions on the extraction of active constituents in Angelica dahurica.The optimized extraction process parameters were 450 W as the microwave power,10 min as the radiation time,30 min as dipping time,1∶4 as the ratio of raw material to solvent,95% as the solvent concentration,40 mesh as the pulverized degree.CONCLUSION The established models and optimized parameters are proved to be reasonable.