文献类型：期刊文献

中文题名：Pressure Gradient Control Strategies Based on Disturbance Rejection for Typical Pharmaceutical Cleanrooms

英文题名：Pressure Gradient Control Strategies Based on Disturbance Rejection for Typical Pharmaceutical Cleanrooms

作者：Chunwang Li[1];Xiaojun Ma[1];Chun-E Huang[2]

第一作者：李春旺

机构：[1]College of Biochemical Engineering, Beijing Union University, Beijing, China;[2]Institute of Fundamental and Interdisciplinary Sciences, Beijing Union University, Beijing, China

第一机构：北京联合大学生物化学工程学院

年份：2021

卷号：9

期号：3

起止页码：555-564

中文期刊名：世界工程和技术（英文）

外文期刊名：World Journal of Engineering and Technology

语种：英文

中文关键词：Pressure Gradient;Pharmaceutical Cleanrooms;Airlock;Active-Disturbance-Rejection-Control;PI Control

外文关键词：Pressure Gradient;Pharmaceutical Cleanrooms;Airlock;Active-Disturbance-Rejection-Control;PI Control

摘要：Keeping pressure gradient is an excellent approach to prevent the reveal of?airflow direction and cross infection in manufacturing circumstances of pharmaceutical cleanrooms, thus how to keep cleanroom’s pressure is critical. In?the paper, we study a positive pressure pharmaceutical cleanroom system which is composed by a cleanroom and an airlock. We divide the system’s disturbances into step disturbance, ramp disturbance and sine wave disturbance.?We design its pressure gradient control strategies, including CAV control, PID control and active-disturbance-rejection-control. We build the system’s model and make simulations based on Matlab/Simulink software platform. Results show that active-disturbance-rejection-control algorithm has good capabilities for shorter responding time and lower overshot of the pressure gradient. The results reveal that active-disturbance-rejection-control method has good control performances in responding time, accuracy and disturbance rejection.
Keeping pressure gradient is an excellent approach to prevent the reveal of?airflow direction and cross infection in manufacturing circumstances of pharmaceutical cleanrooms, thus how to keep cleanroom’s pressure is critical. In?the paper, we study a positive pressure pharmaceutical cleanroom system which is composed by a cleanroom and an airlock. We divide the system’s disturbances into step disturbance, ramp disturbance and sine wave disturbance.?We design its pressure gradient control strategies, including CAV control, PID control and active-disturbance-rejection-control. We build the system’s model and make simulations based on Matlab/Simulink software platform. Results show that active-disturbance-rejection-control algorithm has good capabilities for shorter responding time and lower overshot of the pressure gradient. The results reveal that active-disturbance-rejection-control method has good control performances in responding time, accuracy and disturbance rejection.