文献类型：会议论文

英文题名：Synthesis,Characterization, and Antibacterial Activity of Quaternized of N-aromatic Chitosan Derivatives

作者：Han Yongping[1];Lin Qiang[1]

第一作者：韩永萍

通讯作者：Han, YP[1]

机构：[1]Beijing Union Univ, Biochem Engn Coll, Beijing 100023, Peoples R China

第一机构：北京联合大学生物化学工程学院

通讯机构：[1]corresponding author), Beijing Union Univ, Biochem Engn Coll, Beijing 100023, Peoples R China.|[1141726]北京联合大学生物化学工程学院;[11417]北京联合大学;

会议论文集：2nd International Conference on Applied Mechanics and Mechanical Engineering (ICAMME 2011)

会议日期：OCT 08-09, 2011

会议地点：Sanya, PEOPLES R CHINA

语种：英文

外文关键词：Chitosan; Antibacterial activity; Quaternized N-aromatic chitosan derivatives

摘要：The quatemized of N-aryl chitosan (CTS) derivatives containing different aromatic moieties were synthesized by two steps, N-aromatic Schiff and the quatemization. The chemical structures of all chitosan derivatives, N- vanillin Schiff's base chitosan (NVCh), N- cinnamaldehyde Schiff's base chitosan (NCCh), N- benzaldehyde Schiff's base CTS (NBCh), and their quatemized of N- aromatic CTS derivatives were characterized by ATR-FTIR. The water solubility of the N-aromatic Schiff's base CTS derivatives had very poor water solubility. But after quaternized, the water solubility of CTS derivatives was obviously improved. The antibacterial studies of these CTS derivatives were carried out by the inhibition zone diameters methods against E.coli (Gram-negative), S.aurueus and P.aeruginosa (Gram-positive) bacteria, and against V.Aspergillus niger (fungal). It was found that the quatemized NVSCTS showed higher antibacterial activity than quaternized NCCh and quatemized NVBCh at the almost same DQ and ES level. In comparison to each of the chemical structure, it was found that the phenol hydroxyl group effect on antibacterial activity was even higher than that of positive charge density of CTS.