文献类型：期刊文献

英文题名：Rat intestinal homogenate and pancreatic juice can induce the Z-isomerization of all-E-lycopene in vitro

作者：Huang, Jin[1,2];Hui, Bodi[1]

第一作者：Huang, Jin

通讯作者：Hui, BD[1]

机构：[1]Beijing Union Univ, Dept Food Sci, Beijing 100023, Peoples R China;[2]COFCO Nutr & Hlth Res Inst Co Ltd, Beijing 102209, Peoples R China

第一机构：北京联合大学生物化学工程学院食品科学系

通讯机构：[1]corresponding author), Beijing Union Univ, Dept Food Sci, Beijing 100023, Peoples R China.|[11417146]北京联合大学生物化学工程学院食品科学系;[11417]北京联合大学;[1141726]生物化学工程学院;

年份：2020

卷号：10

期号：1

外文期刊名：SCIENTIFIC REPORTS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000543417700006)】；

基金：We would like to take this opportunity to express our sincere gratitude to the External Cooperation Project of the Beijing Natural Science Foundation (No. KZ200511417020) for its financial support on this project.

语种：英文

摘要：Lycopene is one of the carotenoids often consumed by humans in their diet. Although lycopene exists mainly in the form of the all E-isomer in foods, the considerable quantity of its Z-isomers is found in the human plasma and liver. This observation suggested that the lycopene all-E-isomer was converted into Z-isomers in the human body. In this study, the Z-isomerization of the all-E-isomer was induced in vitro by the pancreatic juice and small intestinal homogenate of male rats under the conditions of 37 degrees C, pH=7.5, nitrogen and darkness, as well as shaking. After 2hours, the proportion of the all E-isomer decreased to 25% and Z-isomer amounts increased relatively. The converted products were identified as 5, 9, and 11 Z-isomers by electronic absorption spectroscopy and mass spectrometry (MS). The observations from this experiment suggested that the Z-isomerization site of the lycopene all E-isomer was located in the small intestinal wall of the rat.