文献类型：期刊文献

英文题名：Optimization of L-lactic acid production by fermentation of Huaimi dregs

作者：Zhang, Jingsheng[1];Guo, Zhiyuan[1];Liu, Bingchen[1];Wang, Yue[1,2];Yu, Na[1];Huo, Qing[1,2]

第一作者：张景胜

通讯作者：Huo, Q[1];Huo, Q[2]

机构：[1]Beijing Union Univ, Biochem Engn Coll, Dept Biomed, Beijing, Peoples R China;[2]Beijing Union Univ, Beijing Key Lab Biomass Waste Resource Utilizat, Beijing, Peoples R China

第一机构：北京联合大学生物化学工程学院

通讯机构：[1]corresponding author), Beijing Union Univ, Biochem Engn Coll, Dept Biomed, Beijing, Peoples R China;[2]corresponding author), Beijing Union Univ, Beijing Key Lab Biomass Waste Resource Utilizat, Beijing, Peoples R China.|[11417]北京联合大学;[1141726]北京联合大学生物化学工程学院;

年份：2018

卷号：32

期号：2

起止页码：357-365

外文期刊名：BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT

收录：;EI(收录号：20171903653623);Scopus(收录号：2-s2.0-85019052044);WOS:【SCI-EXPANDED(收录号:WOS:000428673600013)】；

基金：This work was supported by the National Natural Science Foundation of China [grant number 11475020], [grant number 8151114029]; Building Virtual Teaching and Researching Team to Enhance Teaching Quality and Project [grant number PXM2016-014209-000023].

语种：英文

外文关键词：Huaimi; lactic acid; Rhizopus oryzae

摘要：Utilization of waste dregs, e.g. Huaimi dregs, is an important issue. Huaimi is a traditional Chinese medicine and 20,000 tons of dregs are annually produced. This study optimized the production of L-lactic acid through solid-state fermentation of Huaimi dregs using uniform and orthogonal experimental designs. Among three tested parameters, fermentation time and substrate ratio (wheat bran:Huaimi dregs) were found to have a significant effect on the production of lactic acid. Using fermentation time of 41.6 h, substrate ratio of 4.26:1, inoculum size of 6.1% and fermentation temperature of 28 degrees C, 1 kg Huaimi dregs could produce 286.6 mg lactic acid.