文献类型：期刊文献

中文题名：纳滤纯化低聚壳聚糖制备液

英文题名：Nano-filtration purification of chitooligosaccharides solution

作者：韩永萍[1];林强[1]

第一作者：韩永萍

机构：[1]北京联合大学生物化学工程学院

第一机构：北京联合大学生物化学工程学院

年份：2012

卷号：32

期号：4

起止页码：75-80

中文期刊名：膜科学与技术

外文期刊名：Membrane Science and Technology

收录：CSTPCD;;北大核心:【北大核心2011】；CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：纳滤膜;纯化;低聚壳聚糖

外文关键词：nano-filtration; purification; chitooligosaccharide

摘要：对低聚壳聚糖制备液进行了纳滤纯化研究.试验确定纳滤的最佳操作条件为35～40℃、操作压力为1.0MPa,制备液在纳滤之前还应稀释2.5倍,间歇恒容渗滤过程的每一运行周期的最优浓缩倍数为1.5倍.在该条件运行下,制备液中的单糖和大部分二糖及一价盐离子被脱出,高活性低聚壳聚糖的纯度高达92%,料液体积浓缩接近2倍.
The desalination and purification of chitooligosaccharides（COS） solution were investigated by using nano-filtration （NF）. The optimal operation conditions of COS solution NF purified were obtained as follows： 35-40 ℃, 1.0 MPa operation pressure, COS solution diluted 2. 5 times as the feed solution of NF, and the optimal solution volume concentration factor of a period of the batch constant volume diafiltration process was 1.5. Under these conditions, the monosaccharide and most of disaccharide and monovalent salts were removed from COS solution by NF, and the purity of high biological activity COS was up to 92%, at the same time the volume was condensed to a half of the initial feed solution.