文献类型：期刊文献

中文题名：以壳聚糖为载体的药物新剂型

英文题名：New Dosage Forms Based on Chitosan as Drug Carriers

作者：李若慧[1];程艳玲[1]

第一作者：李若慧

机构：[1]北京联合大学生物化学工程学院

第一机构：北京联合大学生物化学工程学院

年份：2008

卷号：22

期号：3

起止页码：30-34

中文期刊名：北京联合大学学报

语种：中文

中文关键词：新剂型;药物载体;壳聚糖

外文关键词：new dosage forms; drug carrier; chitosan

摘要：在以壳聚糖作为载体的药物新剂型中,壳聚糖在减少给药次数、降低药物毒副作用、提高药物疗效等方面具有重要作用,综述了以壳聚糖为药物载体的新型制剂的各种类型和特性,主要包括缓控释制剂、结肠靶向制剂、纳米制剂等,并对其发展趋势进行了展望。
As drug carriers, chitosan has played an important role in the less administration frequency, lowtoxicity, and cure efficiency enhancement in new dosage forms. In this article, the recent progress in the category and properties of some new dosage forms based on chitosan as drug carriers has been reviewed, including sustained-control release preparation, colon target preparation, nanopartiele preparation, et al. Furthermore, their advance in the future was also introduced briefly.