文献类型：期刊文献

中文题名：主动脉瓣部分关闭和完全开放的有限元分析

英文题名：Finite Element Analysis on Partially Closed and Fully Opened Aortic Valve

作者：刘桂梅[1];潘友联[2];付文宇[3];乔爱科[1]

第一作者：刘桂梅

机构：[1]北京工业大学生命科学与生物工程学院,北京100124;[2]北京工业大学机械工程与应用电子技术学院,北京100124;[3]北京联合大学机器人学院,北京100020

第一机构：北京工业大学生命科学与生物工程学院,北京100124

年份：2018

卷号：0

期号：2

起止页码：95-100

中文期刊名：医用生物力学

外文期刊名：Journal of Medical Biomechanics

收录：CSTPCD;;Scopus;北大核心:【北大核心2017】；CSCD:【CSCD2017_2018】；PubMed;

基金：国家自然科学基金项目(11472023);中国博士后科学基金项目(2016M600025)

语种：中文

中文关键词：主动脉瓣;边界条件;有限元分析;数值模拟

外文关键词：aortic valve;boundary condition;finite element analysis;numerical simulation

摘要：目的探究不同的初始状态设置对瓣膜仿真计算的影响。方法创建初始状态分别为主动脉瓣部分关闭和完全开放的二维结构模型,对瓣膜和主动脉侧、心室侧的血管壁施加随时间变化的压力载荷,采用有限元法研究在两种不同初始状态设置下瓣膜关闭时的最大应力、对合长度和接触力。结果以完全开放为初始状态的模型在瓣膜关闭时的应力和接触力更大,瓣膜闭合程度较差,周期性循环中应力和闭合程度的变化较大;部分关闭为初始状态下瓣膜在关闭时的应力和接触力小,闭合程度较好,周期性循环中应力和闭合程度的变化小。结论在初始状态为部分关闭时,计算过程的稳定性和瓣膜的闭合程度较好,在进行数值模拟计算时可以给予更多的考虑。研究结果可为瓣膜和主动脉根部生物力学机制的研究提供参考。
Objective To explore the effect of different initial state setting on a valve simulation. Methods Twodimensional structural models were established with the initial state of the aortic valve being partially closed in one model and fully opened in the other. The time-dependent load was applied to the valve and the vessel wall of the aortic and the ventricle sides. The finite element method was used to study the maximum stress,the length of the joint,and the contact force of the closed aortic valve under two different initial states. Results The stress and contact force of the aortic valve were relatively large at the closed position when the initial state was fully opened.The closure degree of the valve was low,and the variations in stress and closure degree were large during the periodic cycle. The stress and contact force of the valve were relatively small when the aortic valve was partially closed. The closure degree was high,and the variations in stress and closure degree of the aortic valve were small during the periodic cycle. Conclusions In the case of the aortic valve partially closed in the initial state,the stability of the calculation process and the closure degree of the valve were relatively high,which should be given more consideration in numerical simulation. The results can be used to study the mechanical behavior of the valve and the biomechanical mechanism of the aortic root.