文献类型：期刊文献

英文题名：The arginine vasopressin V1b receptor gene and prosociality: Mediation role of emotional empathy

作者：Wu, Nan[1];Shang, Siyuan[2];Su, Yanjie[2]

第一作者：吴南

通讯作者：Su, YJ[1]

机构：[1]Beijing Union Univ, Peking Univ, Teachers Coll, Dept Psychol, Beijing, Peoples R China;[2]Peking Univ, Dept Psychol, Beijing, Peoples R China

第一机构：北京联合大学师范学院

通讯机构：[1]corresponding author), Peking Univ, Dept Psychol, 5 Yiheyuan Rd, Beijing 100871, Peoples R China.

年份：2015

卷号：4

期号：3

起止页码：160-165

外文期刊名：PSYCH JOURNAL

收录：;Scopus(收录号：2-s2.0-84942326680);WOS:【SSCI(收录号:WOS:000214612800006)】；

基金：This research was supported by the National Natural Science Foundation of China (31170995, 31371040) and the National Basic Research Program (973 Program: 2010CB833904).

语种：英文

外文关键词：AVPR1B gene; emotional empathy; empathy; prosociality

摘要：The vasopressin V1b receptor (AVPR1B) gene has been shown to be closely associated with bipolar disorder and depression. However, whether it relates to positive social outcomes, such as empathy and prosocial behavior, remains unknown. This study explored the possible role of the AVPR1B gene rs28373064 in empathy and prosociality. A total of 256 men, who were genetically unrelated, non-clinical ethnic Han Chinese college students, participated in the study. Prosociality was tested by measuring the prosocial tendencies of cognitive and emotional empathy using the Interpersonal Reactivity Index (IRI). The single nucleotide polymorphism (SNP), rs28373064, was genotyped using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis. The results suggest that the AVPR1B gene rs28373064 is linked to emotional empathy and prosociality. The mediation analysis indicated that the effect of the AVPR1B gene on prosociality might be mediated by emotional empathy. This study demonstrated the link between the AVPR1B gene and prosociality and provided evidence that emotional empathy might mediate the relation between the AVPR1B gene and prosociality.