文献类型：期刊文献

中文题名：微波辅助萃取三棱中甘露醇的工艺优化研究

英文题名：Optimization for Microwave Extraction Process for Mannitol from Sparganium stoloniferum with Uniform Design and Response Surface Analysis

作者：刘红梅[1]

第一作者：刘红梅

机构：[1]北京联合大学生物化学工程学院

第一机构：北京联合大学生物化学工程学院

年份：2007

卷号：18

期号：12

起止页码：3017-3019

中文期刊名：时珍国医国药

外文期刊名：Lishizhen Medicine and Materia Medica Research

收录：北大核心:【北大核心2004】；CSCD:【CSCD_E2011_2012】；

语种：中文

中文关键词：反相高效液相色谱;甘露醇;超临界萃取;均匀设计

外文关键词：RP - HPLC; Sparganium stoloniferum ; Response surface analysis ; Uniform design

摘要：目的优化三棱中甘露醇的微波辅助萃取工艺。方法以甘露醇含量为响应指标,通过均匀试验设计,采用二次响应曲面和通径分析并结合单因素实验优化三棱中甘露醇的微波辅助萃取工艺。结果获得的响应曲面方程在α<0.01的水平上显著,优化的萃取工艺参数为:微波功率1 400 W,辐射时间30 min,浸泡时间120 min,固液比为1∶6,乙醇浓度为45%,模型预测值的相对误差小于1%。结论获得的响应曲面方程在α<0.01的水平上显著,优化的萃取工艺参数为:微波功率1 400 W,辐射时间30 min,浸泡时间120 min,固液比为1:6,乙醇浓度为45%,模型预测值的相对误差小于1%。
Objective To optimize microwave extraction process of mannitol from Sparganium stoloniferum. Methods Guided by the contents of mannitol in Sparganium stoloniferum, uniform design, response surface analysis and path analysis were used to optimize microwave extraction process by combining with single factor experiment. Results Obtained response surface equation is notable at the level a 〈 0.01 and the relative error of the predicted value from the model was smaller than 1%. The optimized process was established as following ：1400 W as radiation power, 30 min as radiation time, 120 min as dipping time and 6 times as the ratio of solid to solvent and 45% of alcohol as extractor. Conclusion The established model is quite notable and has quite high prediction precision and the yield of mannitol extracted by the optimized microwave extraction process is the highest as compared with other processes.