文献类型：期刊文献

中文题名：魔芋低聚糖对小鼠肠道菌群的调节作用

英文题名：Regulation effect of konjac oligosaccharide on gut microbiota in mice

作者：王文娟[1];贺青华[1];魏芬芬[1];魏嵘[1];张波[1]

第一作者：王文娟

机构：[1]北京联合大学生物化学工程学院生物活性物质与功能食品北京市重点实验室

第一机构：北京联合大学生物化学工程学院|北京联合大学应用文理学院

年份：2017

卷号：36

期号：10

起止页码：135-138

中文期刊名：中国酿造

外文期刊名：China Brewing

收录：CSTPCD;;北大核心:【北大核心2014】；

基金："十二五"国家科技支撑计划课题(2012BAD33B06);校企合作课题

语种：中文

中文关键词：魔芋低聚糖;小鼠;肠道菌群

外文关键词：konjac oligosaccharide; mice; gut microbiota

摘要：该实验研究了魔芋低聚糖(KOGM)对小鼠肠道菌群的调节作用。以不同剂量魔芋低聚糖连续灌胃小鼠35 d,测定血清生化指标,无菌条件下取小鼠粪便培养肠道菌群。结果表明,与对照组比较,魔芋低聚糖高剂量组(2.00 g/kg体质量)小鼠粪便中双歧杆菌和乳杆菌数量(对数值分别为3.65、3.81)显著增加(P<0.05),肠杆菌和产气杆菌数量无显著性变化(P>0.05);结肠内容物中乙酸、丙酸以及丁酸的含量(6.51 mmol/100 g、1.69 mmol/100 g、3.83 mmol/100 g)显著增加(P<0.05)。说明魔芋低聚糖对小鼠肠道菌群有较好调节作用。
The effect of konjac oligosaccharide on the gut microbiota in mice was evaluated. Konjac oligosaccharide was continuously gavaged for 35 d and the serum biochemical parameters were measured. Rat fecal and culture gut microbiota was extracted under sterile condition. The results showed that fecal Bifidobacterium and Lactobacillus levels in konjac oligosaccharide high dose group （2.00 g/kg BW） were significantly higher （P〈0.05） than that in control group, and the log value of the bacteria was 3.65 and 3.81, respectively. There was no significant change in Enterbacter and Aerobacter counts （P〈 0.05）. The acetic acid, propionic acid and butyric acid contents in colon was significanly increased （P〈 0.05）, which was 6.51 mmol/100 g, 1.69 mmol/100 g and 3.83 mmol/100 g, respectively. The results demonstrated that konjac oligosaccharide had positive regulation effect on gut microbiota in mice.