文献类型：期刊文献

英文题名：Methodological study on endogenous calcium absorptivity using rats and Ca-41 tracing

作者：Zhang, Hui[1,2];Dou, Liang[1];Wang, Xiao-Ming[1];Mi, Sheng-Quan[3];Zhao, Qing-Zhang[1];Jiang, Shan[1];He, Ming[1]

第一作者：Zhang, Hui

通讯作者：He, M[1]

机构：[1]China Inst Atom Energy, Beijing 102413, Peoples R China;[2]Heilongjiang Acad Sci, Tech Phys Inst, Harbin 150086, Heilongjiang, Peoples R China;[3]Beijing Union Univ, Dept Biol, Coll Appl Arts & Sci, Beijing 100083, Peoples R China

第一机构：China Inst Atom Energy, Beijing 102413, Peoples R China

通讯机构：[1]corresponding author), China Inst Atom Energy, Beijing 102413, Peoples R China.

年份：2018

卷号：29

期号：4

外文期刊名：NUCLEAR SCIENCE AND TECHNIQUES

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000429382600011)】；

基金：This work was supported by the National Nature Science Foundation of China (No. 11375272).

语种：英文

外文关键词：Endogenous calcium absorptivity; Ca-41 tracer; Accelerator mass spectrometry measurement

摘要：Elemental calcium plays an important role in human physiology. In order to study the relationship between Ca-intake, Ca-chemical formulation, and Ca-absorptivity, a balance experiment using a Ca-41 tracer technique in SD rats was conducted to measure the endogenous fecal calcium and true absorption of calcium. Apparent absorption of calcium was measured as a control to the endogenous calcium labeling experiment. These results show that by using Ca-41 labeled endogenous calcium in vivo, researchers could obtain the true calcium absorption data without extrinsic labeling. Therefore, the method was not affected by the chemical structure or type of calcium supplement and might be used in evaluating the absorptivity of marketed calcium supplements.