文献类型：期刊文献

英文题名：Chemical characterization of the polar antibacterial fraction of the ethanol extract from Rosmarinus officinalis

作者：Zhong, Xiangjian[1]; Wang, Xin[1]; Zhou, Na[1]; Li, Jinjie[1]; Liu, Jiachen[1]; Yue, Jianyu[1]; Hao, Xiaomeng[2]; Gan, Maoluo[2]; Lin, Pengcheng[3]; Shang, Xiaoya[1]

第一作者：Zhong, Xiangjian

通讯作者：Gan, Maoluo

机构：[1] Beijing Key Laboratory of Bioactive Substances and Functional Foods, Beijing Union University, Beijing, 100191, China; [2] Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China; [3] Key Laboratory for Qinghai-Tibet Plateau Phytochemistry of Qinghai Province, Qinghai University for Nationalities, Xining, 810000, China

第一机构：北京联合大学生物化学工程学院|北京联合大学应用文理学院

通讯机构：[2]Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China

年份：2021

卷号：344

外文期刊名：Food Chemistry

收录：EI(收录号：20204909566806);Scopus(收录号：2-s2.0-85096880025)

语种：英文

外文关键词：Bacteriology

摘要：Rosmarinus officinalis L. has been widely used as a spice to extend the shelf life of foods. Most studies in the literature indicate that its essential oil is its major antibacterial component. In this study, a polar fraction from rosemary exhibited considerably stronger antibacterial activity against Bacillus subtilis than its essential oil. Guided by rapid characterization of the chemical compositions based on UPLC-Orbitrap-MS/MS, further investigation resulted in the isolation and identification of sixteen compounds. Among them, two new and six known compounds were identified in rosemary for the first time. Most isolated compounds exhibited significant antibacterial activities with minimum inhibitory concentration values of 2–128 μg/mL; however, these activities were weaker than that of the polar fraction. Thus, the polar fraction demonstrated a promising potential to serve as a food additive, as an alternative to the essential oil, because of its stronger antibacterial activity. ? 2020