文献类型：期刊文献

英文题名：A turn-on fluorescence chemosensor for Al3+, F- and CN- ions, and its application in cell imaging

作者：Ding, Wei-Hua[1]; Wang, Dan[1]; Zheng, Xiang-Jun[1]; Ding, Wan-Jian[2]; Zheng, Jian-Quan[3]; Mu, Wei-Hua[4]; Cao, Wei[1]; Jin, Lin-Pei[1]

第一作者：Ding, Wei-Hua

通讯作者：Zheng, Xiang-Jun

机构：[1] Beijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, 100875, China; [2] Key Laboratory of Theoretical and Computational Photochemistry, Ministry of Education, Beijing Normal University, Beijing, 100875, China; [3] Beijing Key Laboratory for Bioactive Substances and Functional Foods, Beijing Union University, Beijing, 100191, China; [4] Faculty of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, 650092, China

第一机构：Beijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, 100875, China

年份：2015

卷号：209

起止页码：359-367

外文期刊名：Sensors and Actuators, B: Chemical

收录：EI(收录号：20145200379452);Scopus(收录号：2-s2.0-84919726008)

语种：英文

外文关键词：Aluminum compounds - Crystal structure - Excited states - Physiology - Single crystals - Addition reactions - Atoms - Coordination reactions - Absorption spectroscopy - X ray diffraction - Hydrogen bonds - Nickel compounds - Fluorine compounds - Ions

摘要：A chemosensor 3-[(2-hydroxybenzylidene)-amino]-1H-pyridin-2-one (HL) for multi-ions was synthesized and characterized by single-crystal X-ray diffraction. HL is a turn-on fluorescence chemosensor for Al3+, F-, and CN- ions in DMSO. F- and CN- anions could be further distinguished by the ratiometric absorption spectrometry method. Job plot and 1H NMR data showed that the binding stoichiometries of HL with Al3+, F-, or CN- all were 1:1. Further observations of 1H NMR titration and ESI-MS showed that the possible fluorescent species of Al3+ with HL was [AlL(OH)(DMSO)2]+ in DMSO. The spectroscopic observations of the Al(III) complex showed that the two oxygen atoms and one imine nitrogen atom of HL were coordinated to the Al(III) ion. While the crystal structure of the Ni(II)-L complex confirmed the tridentate coordination mode of HL in the complexes. The experimental results revealed that HL and F- ion formed hydrogen bond in DMSO, while CN- attacked the carbon atom at -CN of HL to undergo a nucleophilic addition. The theoretical calculations confirmed that HL showed very weak fluorescence because of the excited-state intramolecular proton transfer (ESIPT). The turn-on sensing of HL to Al3+, F-, and CN- ions arose from the inhibition of ESIPT. MTT tests showed that HL was low toxic to cells. Also, HL could probe intracellular Al3+ and F- ions by bioimaging. ? 2014 Elsevier B.V. All rights reserved.