文献类型：期刊文献

中文题名：微生物合成PHA的研究进展

英文题名：Research Advances in Microbial Synthesis of PHA

作者：柳杰[1];王晚晴[1,2];刘文慧[1,2];华威[1,2];程艳玲[1,2]

第一作者：柳杰

机构：[1]北京联合大学生物化学工程学院;[2]生物质废弃物资源化利用北京市重点实验室

第一机构：北京联合大学生物化学工程学院

年份：2017

卷号：0

期号：2

起止页码：16-21

中文期刊名：高分子通报

外文期刊名：Polymer Bulletin

收录：CSTPCD;;北大核心:【北大核心2014】；CSCD:【CSCD2017_2018】；

基金："863计划"课题(2015AA020202;2014AA022002);国家国际科技合作课题(2015DFA60170;2014DFA61040);北京市大学科技园项目"微波裂解纤维素类生物质多联产关键技术";北京市教育委员会科技计划一般项目(122139916080101-010);北京市教育委员会科技计划面上项目(KM201511417011)

语种：中文

中文关键词：聚羟基脂肪酸酯;微生物;发酵

外文关键词：Polyhydroxyalkanoate ; Microorganism; Fermentation

摘要：传统化石来源的塑料虽然给人类的生活带来了许多便利,但这些难降解塑料不断地堆积在环境中,导致了全球环境恶化、固体垃圾难处理等问题。因此,可生物降解塑料的研究与开发成为了近年来研究的重点。聚羟基脂肪酸酯(PHA)是一类微生物合成的高分子生物聚脂,具有良好的生物可降解性、生物相容性等特殊性质,可替代传统化石塑料成为新型生物材料,有很好的环境效应与应用前景,目前其作为心脏瓣膜材料的研究在动物实验中已取得了很好的结果。在本文中,作者结合国内外合成PHA的相关研究,对合成PHA微生物的种类及其发酵工艺进行了总结,并对其未来发展进行了展望。
Traditional fossil plastics has brought a lot of convenience to human, but these refractory plastic are continuous accumulating in the environment, leading to the deterioration of global environment, the solid waste disposal problems. Therefore, the research and development of biodegradable plastic has become the main point in recent years. Polyhydroxyalkanoate （PHA）, a microbially synthesized polyesters with good biological degradability, biocompatibility and other special properties, can become the new biological materials alternative to traditional fossil plastic. Also PHA, as a heart valve tissue material, has achieved very good results in animal trials. It has shown good environmental effects and some promises. In this paper, the microorganisms in synthesis of PHA and their fermentation technology were reviewed combining with synthesis of PHA related research at home and abroad, then its development is prospected.