文献类型：期刊文献

英文题名：Preparation, structure characterization, and specific gut microbiota properties related to anti-hyperlipidemic action of type 3 resistant starch from Canna edulis

作者：Zhang, Chi[1,2,3]; Qiu, Minyi[1,4]; Wang, Ting[2]; Luo, Linglong[1]; Xu, Wenjuan[1]; Wu, Jiahui[1]; Zhao, Fangyuan[1]; Liu, Kaiyang[1]; Zhang, Yuan[3]; Wang, Xueyong[1,2]

第一作者：Zhang, Chi

通讯作者：Zhang, Yuan

机构：[1] School of Chinese Materia Medica, Beijing University of Chinese Medicine, No.11 North 3rd Ring East Road, Chao-Yang District, Beijing, 100029, China; [2] Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Chao-Yang District, Beijing, 100029, China; [3] College of Biochemical Engineering, Beijing Union University, No. 18, Fatou Xili District, Chaoyang District, Beijing, 100023, China; [4] Pharmacy Department, Peking University People's Hospital, No. 11, Xizhimen Street, Xicheng District, Beijing, 100044, China

第一机构：School of Chinese Materia Medica, Beijing University of Chinese Medicine, No.11 North 3rd Ring East Road, Chao-Yang District, Beijing, 100029, China

年份：2021

卷号：351

外文期刊名：Food Chemistry

收录：EI(收录号：20210910009394);Scopus(收录号：2-s2.0-85101662595)

语种：英文

外文关键词：Crystallinity - Enzymatic hydrolysis - Mammals - Starch

摘要：Type 3 resistant starch (RS3) was developed from Canna edulis (Ce) native starch (NS) through dual enzymatic hydrolysis and recrystallization. Thereafter, the processed Ce-RS3 was subjected to systematic characterizations for its structural properties, anti-hyperlipidemic effect, and in vivo gut microbiota modulatory function. The Ce-RS3 content was increased to 49.11% after processing under optimal conditions. Compared with NS, Ce-RS3 maintained its B-type crystallization without introducing new chemical groups. Meanwhile, it displayed coarse surfaces, higher crystallinity, more ordered structures, and a higher proportion of chains with degree of polymerization (DP) 37-100. Ce-RS3 intervention significantly alleviated dyslipidemia in hyperlipidemic mice, which was associated with increased gut microbial diversity and unique microbial enrichment, potentially mediated by its fine structure. These observations are valuable for developing RS3 from C. edulis for prebiotics applications and support the potential strategy that utilizes well-designed RS to modulate specific bacterial populations to improve health. ? 2021 Elsevier Ltd