文献类型：期刊文献

中文题名：维生素E脂质体的制备与性能研究

英文题名：Study on preparation and property of V_E liposome

作者：林强[1];刘国川[1]

机构：[1]北京联合大学生物化学工程学院制药工程研究所

第一机构：北京联合大学生物化学工程学院生物医药系

年份：2006

卷号：29

期号：1

起止页码：22-23

中文期刊名：日用化学品科学

外文期刊名：Detergent & Cosmetics

语种：中文

中文关键词：化妆品;添加剂;维生素E;脂质体;薄膜蒸发

外文关键词：cosmetic; additive; VE; liposome; thin-film evaporator

摘要：采用薄膜蒸发-高压均质法制备维生素E(VE)脂质体,研究了VE脂质体配方中不同成分的比例及水合介质对脂质体包封率的影响。结果表明,VE脂质体载药量越大,包封率越低。胆固醇含量在体系中要适当。最佳的水合介质是磷酸盐缓冲液。采用薄膜蒸发结合高压均质处理法制备的VE脂质体粒径达到120nm,而且比较稳定。
VE liposome was prepared by thin-film evaporator and high pressure homogenization method. The influence of proportion of components in VE liposome and hydration medium on encapsulation efficiency were studied. The results showed that encapsulation efficiency decreased with the increase of VE load capacity. The component of cholesterol must be moderated. The optimizing hydration medium is phosphate buffer solution. The size of VE liposome prepared by this method can reach 120 nm and the property of it is very stable.