文献类型：期刊文献

英文题名：Chemical characterization of the antioxidant and a-glucosidase inhibitory active fraction of Malus transitoria leaves

作者：Lu, Yongchang[1];Wang, Xin[2];Wu, Yong[2];Wang, Zeyu[2];Zhou, Na[2];Li, Jinjie[2];Shang, Xiaoya[2];Lin, Pengcheng[1]

第一作者：Lu, Yongchang

通讯作者：Lin, PC[1];Shang, XY[2]

机构：[1]Qinghai Univ Nationalities, Qinghai Prov Key Lab Phytochemistry Tibetan Platea, Xining 810000, Peoples R China;[2]Beijing Union Univ, Beijing Key Lab Bioact Subst & Funct Foods, Beijing 100191, Peoples R China

第一机构：Qinghai Univ Nationalities, Qinghai Prov Key Lab Phytochemistry Tibetan Platea, Xining 810000, Peoples R China

通讯机构：[1]corresponding author), Qinghai Univ Nationalities, Qinghai Prov Key Lab Phytochemistry Tibetan Platea, Xining 810000, Peoples R China;[2]corresponding author), Beijing Union Univ, Beijing Key Lab Bioact Subst & Funct Foods, Beijing 100191, Peoples R China.|[1141726]北京联合大学生物化学工程学院;[11417]北京联合大学;[114172]北京联合大学应用文理学院;

年份：2022

卷号：386

外文期刊名：FOOD CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000792958800003)】；

基金：This work was supported by the Foundation for Key R&D and Transformation Project of Qinghai Province (No. 2020-NK-171) and Beijing Natural Science Foundation (No. 7214280) .

语种：英文

外文关键词：Malus transitoria; Antioxidant activity; alpha-Glucosidase inhibitory activity; UPLC-Orbitrap-MS/MS; Chemical composition

摘要：Chinese Tibetan tea made from the tender leaves of Malus transitoria is a widely consumed health drink, but there are few reports on its chemical composition and biological activity. In this study, we found that a 50% ethanol extract of M. transitoria had good antioxidant and alpha-glucosidase inhibitory activities in vitro. Guided by in vitro bioassays, chromatographic separation and purification were conducted, and the most active fraction in M. transitoria was determined. UPLC-Orbitrap-MS/MS was used to further quickly and comprehensively characterize the chemical composition. Library searches, MS/MS fragmentation patterns of two isolated reference compounds, and bibliography were used to annotate 81 compounds, of which 2 were new compounds, and 79 were identified from M. transitoria for the first time. This study provides a scientific basis for the development of antioxidant and anti-diabetic functional foods from M. transitoria.