文献类型：期刊文献

英文题名：A novel acylhydrazone-based derivative as dual-mode chemosensor for Al3+, Zn2+ and Fe3+ and its applications in cell imaging

作者：Liao, Zhuang[1]; Liu, Yang[1]; Han, Su-Fang[1]; Wang, Dan[1]; Zheng, Jian-Quan[2]; Zheng, Xiang-Jun[1]; Jin, Lin-Pei[1]

第一作者：Liao, Zhuang

通讯作者：Zheng, Xiang-Jun

机构：[1] Beijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, 100875, China; [2] Beijing Key Laboratory for Bioactive Substances and Functional Foods, Beijing Union University, Beijing, 100191, China

第一机构：Beijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, 100875, China

通讯机构：[1]Beijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, 100875, China

年份：2017

卷号：244

起止页码：914-921

外文期刊名：Sensors and Actuators, B: Chemical

收录：EI(收录号：20170303260487);Scopus(收录号：2-s2.0-85009436202)

语种：英文

外文关键词：Charge transfer - Naphthalene - Excited states - Metal complexes - Physiology - Mass spectrometry - Probes - Aggregates - Fluorophores

摘要：An acylhydrazone-based derivative, 3-hydroxy-N'-(2-hydroxy-1-naphthalene methylene)-2-naphthalene hydrazide (H3L), was synthesized and characterized by elemental analyses, IR,1H NMR and mass spectrum. H3L is non-fluorescent in DMSO. But the fluorescence emission is enhanced obviously via the formation of aggregates in DMSO/H2O mixture. The formed aggregates were confirmed by DLS and SEM. H3L is an aggregation-induced emission (AIE)-active fluorophore. H3L can act as a fluorescence sensor for Al3+and Zn2+in DMSO/H2O (v/v, 9/1) and THF/H2O (v/v, 999/1), respectively. And H3L is also a naked-eye probe for Fe3+in DMSO/H2O (v/v, 9/1). The binding stoichiometry of H3L to both Al3+and Zn2+is 1:1, but that to Fe3+is 2:1. The metal complex species formed in the detection procedure are deduced by Job plot, spectroscopic titrations and ESI–MS to be [AlL(DMSO)2], [Zn(HL)(H2O)] and [Fe(HL)(H2L)]. The detection limit is as low as 3.66?μM for Al3+, 1.01?μM for Zn2+and 0.34?μM for Fe3+. H3L can also be used to detect intracellular Al3+and Zn2+. The sensing event might be attributed to a combinational effect of excited state intramolecular proton transfer (ESIPT) and chelation-enhanced fluorescence (CHEF) mechanism for selective detection of Al3+and Zn2+ions, and ligand-metal charge transfer (LMCT) mechanism for Fe3+ion. ? 2017 Elsevier B.V.