文献类型：期刊文献

英文题名：Cu(II) complex-based fluorescence chemosensor for cyanide in aqueous media

作者：Wang, Dan[1];Zheng, Jian-Quan[1,2];Yan, Xi[1];Zheng, Xiang-Jun[1];Jin, Lin-Pei[1]

第一作者：Wang, Dan

通讯作者：Zheng, XJ[1]

机构：[1]Beijing Normal Univ, Coll Chem, Beijing Key Lab Energy Convers & Storage Mat, Beijing 100875, Peoples R China;[2]Beijing Union Univ, Beijing Key Lab Bioact Subst & Funct Foods, Beijing 100191, Peoples R China

第一机构：Beijing Normal Univ, Coll Chem, Beijing Key Lab Energy Convers & Storage Mat, Beijing 100875, Peoples R China

通讯机构：[1]corresponding author), Beijing Normal Univ, Coll Chem, Beijing Key Lab Energy Convers & Storage Mat, Beijing 100875, Peoples R China.

年份：2015

卷号：5

期号：79

起止页码：64756-64762

外文期刊名：RSC ADVANCES

收录：;EI(收录号：20153201114029);Scopus(收录号：2-s2.0-84938567056);WOS:【SCI-EXPANDED(收录号:WOS:000358786400090)】；

基金：This study is supported by the National Natural Science Foundation of China (20971015) and the Fundamental Research Funds for the Central Universities.

语种：英文

外文关键词：Crystal structure - Fluorescence

摘要：A fluorescent quinazoline derivative, 6-(2,4-dihydroxyphenyl)-5,6-dihydrobenzoimidazo[1,2-c]quinazoline (H2L), was designed and synthesized. Its fluorescence could be quenched by the addition of Cu2+ in an aqueous media. The binding constant for Cu2+ and H2L was determined to be 9.56 x 10(3) M-2 in DMSO/H2O (1 : 1, v/v). The crystal structure of the Cu(II) complex, [Cu(HL1)(Ac)] (1) (H2L1 = 4-{[2-(1H-benzimidazol-2-yl)-phenylimino]-methyl}-benzene-1,3-diol, Ac = acetate), revealed that Schiff base complex 1, H2L1, was formed in the response system of H2L to Cu2+ via Cu2+-assisted C-N bond breakage of the quinazoline ring in H2L. Consequently, complex 1 was used as a turn-on fluorescence chemosensor for the direct detection of CN-, and showed a high selectivity to CN- over a number of anions in the aqueous media, where CN- replaces HL1 in 1 to form [Cu(CN)(x)](2-x) with HL1 then released and the fluorescence recovered. The detection limit for CN- was 4.0 x 10(-6) M. The cell images showed that 1 could be used to detect intracellular CN-.