文献类型：期刊文献

英文题名：Variations in the oxytocin receptor gene and prosocial behavior: moderating effects of situational factors

作者：Wu, Nan[1,2,3];Su, Yanjie[2,3]

第一作者：吴南;Wu, Nan

通讯作者：Su, YJ[1];Su, YJ[2]

机构：[1]Peking Univ, Beijing Union Univ, Teachers Coll, Beijing, Peoples R China;[2]Peking Univ, Sch Psychol & Cognit Sci, 5 Yiheyuan Rd, Beijing 100871, Peoples R China;[3]Peking Univ, Beijing Key Lab Behav & Mental Hlth, 5 Yiheyuan Rd, Beijing 100871, Peoples R China

第一机构：北京联合大学师范学院

通讯机构：[1]corresponding author), Peking Univ, Sch Psychol & Cognit Sci, 5 Yiheyuan Rd, Beijing 100871, Peoples R China;[2]corresponding author), Peking Univ, Beijing Key Lab Behav & Mental Hlth, 5 Yiheyuan Rd, Beijing 100871, Peoples R China.

年份：2018

卷号：13

期号：6

起止页码：687-697

外文期刊名：INTEGRATIVE ZOOLOGY

收录：;Scopus(收录号：2-s2.0-85057487937);WOS:【SCI-EXPANDED(收录号:WOS:000451607100006)】；

基金：This work was supported by the National Natural Science Foundation of China (Grant Nos. 31371040, 81501184 and 31571134)

语种：英文

外文关键词：group membership; oxytocin receptor gene; prosocial behavior; prosocial cost

摘要：Humans are the most prosocial primate species and they often exhibit high levels of prosocial behavior toward genetically unrelated individuals. Traditional evolutionary theories are not sufficient to explain the individual differences and mechanisms related to prosociality. In this study, we focused on the gene-situation interaction in prosocial behaviors, and the patterns of genotype variance related to cooperation and comforting in different situations. We explored the interaction between the oxytocin receptor (OXTR) gene and situations, and the genotype variance under low and high prosociality situations between outgroup and ingroup recipients in a sample of 422 Chinese males. Prosociality was tested by measuring the prosocial tendencies, and prosocial behaviors were tested in cooperation and comforting tasks. OXTR single nucleotide polymorphisms (SNPs) were genotyped using polymerase chain reaction-restriction fragment length polymorphism analysis. The results suggested that the relationship between OXTR SNPs (specifically rs13316193, rs1042778 and rs237887) and prosocial behavior varied across different situations, and that the associations were moderated by the recipient's identity and the prosocial cost. Our findings indicate the action of a moderating mechanism between the OXTR gene and prosocial behaviors according to situational factors.