文献类型：期刊文献

英文题名：Application of analytical and preparative high-speed counter-current chromatography for separation of alkaloids from Coptis chinensis Franch

作者：Yang, Fuquan; Zhang, Tianyou; Zhang, Ren; Ito, Yoichiro

机构：[1]Beijing Inst. of New Technol. A., Beijing 100035, China;[2]Chemical Engineering College, Beijing Union University, Beijing 100029, China;[3]Laboratory of Biophysical Chemistry, Natl. Heart, Lung,/Blood Institute, National Institutes of Health, Bethesda, MD 20892, United States

第一机构：Beijing Inst. of New Technol. A., Beijing 100035, China

年份：1998

卷号：829

期号：1-2

起止页码：137-141

外文期刊名：Journal of Chromatography A

收录：EI(收录号：1999034605046);Scopus(收录号：2-s2.0-0032442586)

语种：英文

外文关键词：Alkaloids; Coptis chinensis Franch; High-speed counter-current chromatography

摘要：Analytical high-speed counter-current chromatography (HSCCC) was used for the systematic selection and optimization of the two-phase solvent system to separate alkaloids from Coptis chinensis Franch. The optimum solvent system thus obtained led to the successful separation of alkaloids from C. chinensis Franch by preparative HSCCC. One batch separation yielded four pure alkaloids, including palmatine, berberine, epiberberine and coptisine from the crude alkaloid extract.