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2010年我国成年人血脂异常流行特点    

Epidemioiogic characteristics of dyslipidemia in Chinese adults in 2010

文献类型:期刊文献

中文题名:2010年我国成年人血脂异常流行特点

英文题名:Epidemioiogic characteristics of dyslipidemia in Chinese adults in 2010

作者:李剑虹[1];王丽敏[1];李镒冲[1];毕宇芳[2];姜勇[1];米生权[3];戴蒙[2];徐瑜[2];宁光[2];赵文华[4]

第一作者:李剑虹

机构:[1]中国疾病预防控制中心慢性非传染性疾病预防控制中心,北京100050;[2]上海交通大学医学院附属瑞金医院内分泌代谢病科;[3]北京联合大学应用文理学院;[4]中国疾病预防控制中心学术出版编辑部

第一机构:中国疾病预防控制中心慢性非传染性疾病预防控制中心,北京100050

年份:2012

卷号:46

期号:5

起止页码:414-418

中文期刊名:中华预防医学杂志

外文期刊名:Chinese Journal of Preventive Medicine

收录:CSTPCD;;Scopus;北大核心:【北大核心2011】;CSCD:【CSCD2011_2012】;PubMed;

基金:中央财政转移支付地方项目

语种:中文

中文关键词:成年人;血脂异常;流行病学研究

外文关键词:Adult ; Dyslipidemia; Epidemiologic studies

摘要:目的 调查2010年中国成年人高胆固醇血症、高低密度脂蛋白胆固醇血症、低高密度脂蛋白胆同醇血症和高甘油三酯血症的患病率,分析其流行特点。方法2010年在全国31个省(区、市)的162个监测点,采用多阶段分层整群随机抽样方法,调查了97409名18岁以上居民。抽取空腹静脉血,进行TC、LDL-C、HDL-C和TG检测。对样本进行复杂加权后,计算高胆固醇血症、高低密度脂蛋白胆同醇血症、低高密度脂蛋白胆固醇血症及高甘油三酯血症患病率。结果经复杂加权后,我国18岁以上居民高胆固醇血症患病率为3.3%,18-44、45-59和≥60岁居民的患病率分别为2.2%、4.7%和4.9%(P〈0.01);男、女分别为3.4%、3.2%(P〉0.05);城市和农村分别为4.2%、2.9%(P〈0.01);东、中、西部分别为4.2%、2.4%和3.1%(P〈0.01)。高低密度脂蛋F1胆固醇血症患病率为2.1%,18-44、45-59和≥60岁居民的患病率分别为1.3%、3.0%和3.6%(P〈0.01);男、女均为2.1%;城市和农村分别为3.0%、1.8%(P〈0.01);东、中、西部分别为2.9%、1.5%和1.8%(P〈0.01)。低高密度脂蛋白胆固醇血症患病率为44.8%,18-44、45-59和≥60岁居民的患病率分别为46.9%、42.6%和41.2%(P〈0.01);男、女分别为50.6%、38.9%(P〈0.01);城市和农村分别为45.4%、44.6%(P〈0.05);东、中、西部分别为43.5%、43.3%和48.6%(Jp〈0.01)。,高片油三酯血症患病率为11.3%,18-44、45-59和≥60岁居民的患病率分别为10.1%、14.2%和10.8%(P〈0.01);男、女分别为13.8%、8.6%(P〈0.01);城市和农村分别为12.1%、10.9%(P〈0.01);东、中、西部分别为11.0%、11.7%和11.2%(P〈0.05)。结论我国成年人血脂异常以低高密度脂蛋白胆固醇血症、高甘油三酯血症为主。
Objective To understand the prevalence of hypercholesterolemia, high blood low density lipoprotein cholesterol, low blood high density lipoprotein cholesterol and hypertriglyceridemia among Chinese adults in 2010. Methods Levels of triglyceride (TG) , low density liprotein-cholesterol ( LDL-C ) , high density lipoprotein-cholesterol(HDL-C) and total cholesterol(TC) were determined in fasting serum for subjects who were selected by multi-stage stratified cluster random sampling in from 162 surveillance points of 31 provinces in 2010. Prevalence of hypercholesterolemia, high blood LDL-C, low blood HDL-C and hypertriglyceridemia of 97 409 subjects was analyzed. Results After the complex weighting, prevalence of hypereholesterolemia in Chinese adults was 3.3% , with 2.2% , 4. 7% and4. 7% in the groups of 18 -44, 45 - 59 and over 60 years old ( P 〈 0. 01 ) , respectively, 3.4% and 3.2% in males and females ( P 〉 0.05), respectively, 4. 2% and 2.9% in urban and rural areas (P〈0.01), 4. 2%, 2. 4% and 3.1% in areas of east, central and west( P 〈0.01 ). Prevalence of high blood LDL-C was 2. 1% , with 1.3% , 3.0% and 3.6% in the groups of 18 -44, 45 -59 and over 60 years old(P 〈0. 01 ) , respectively, 2. 1% in both males and females (P 〉0. 05) , 3.0% and 1.8% in urban and rural areas (P 〈0. 01 ) , and 2.9% , 1.5% and 1. 8% in areas of east, central and west( P 〈 0. 01 ) , respectively. Prevalence of low blood HDL-C was44. 8%, with 46. 9%, 42. 6% and 41.2% in the groups of 18 -44, 45 -59 and over 60 years old(P 〈 0. 01 ) , 50. 6% and 38.9% in males and females (P 〈0. 01 ) , respectively, 45.4% and 44. 6% in urban and rural areas ( P 〈 0. 05 ) , and 43.5% , 43.3% and 48.6% in areas of east, central and west ( P 〈 0. 01 ). Prevalence of hypertriglyeeridemia was 11.3% , with 10. 1% , 14. 2% and 10. 8% in the groups of 18 -44, 45 -59 and over 60 years old (P 〈0. 01 ) , respectively, 13.8% and 8.6% in males and females (P 〈0. 01) , respectively, 12. 1% and 10. 9% in urban and rural areas (P 〈0. 01), and 11.0% , 11.7% and 11.2% in areas of east, central and west ( P 〈 0.05 ) . Conclusion Low blood HDL-C and hypertriglyceridemia are two major types of dyslipidemia in Chinese adults.

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