文献类型：期刊文献

英文题名：Selective Esterification and Antioxidant Activity of Rutin

作者：Huo, Qing[2];Gu, Xuemei[1];Lin, Qiang[2];Sun, Yujiao[2];Xu, Chenxia[2];Xiao, Lei[2]

第一作者：霍清

通讯作者：Gu, XM[1]

机构：[1]Beijing Mil Gen Hosp, Beijing 100700, Peoples R China;[2]Beijing Union Univ, Biochem Engn Coll, Beijing 100023, Peoples R China

第一机构：Beijing Mil Gen Hosp, Beijing 100700, Peoples R China

通讯机构：[1]corresponding author), Beijing Mil Gen Hosp, Beijing 100700, Peoples R China.

年份：2011

卷号：23

期号：8

起止页码：3413-3416

外文期刊名：ASIAN JOURNAL OF CHEMISTRY

收录：;Scopus(收录号：2-s2.0-79958057177);WOS:【SCI-EXPANDED(收录号:WOS:000293193400026)】；

基金：This work was supported by Biochemical Engineering College of Beijing Union University Subject Construction Projects.

语种：英文

外文关键词：Rutin; Esterification modification; Thin layer separation; Oxidation resistance

摘要：Rutin is a natural medicine which is widely presented in plants. Modified by the esterification of rutin in the introduction of long hydrocarbon chain molecules, in order to increase its solubility and stability in the lipophilic, thus increasing the antioxidant activity. This paper reports the reaction solvents, acyl donor chain length, molecular sieve and enzyme. Experimental results show that tert-amyl alcohol is the best solvent for the reaction; Rhizopus arrhizus whole-cell lipase or Lipase Novozym435 is used as biological catalyst, enzyme; the molar ratio of Lauric acid:rutin is 5:1, the reaction temperature is 60 degrees C, the reaction time is ca. 96 h, within the esterification, we should add molecular sieve in order to increase the esterification conversion. Antioxidant effect is tested by the ultraviolet spectrophotometer. The ester has stronger scavenging effect for (center dot)OH and (center dot)O(2)(-) than rutin. So the ester has more antioxidant capacity than rutin and mannitol.