详细信息
中国北方汉族人群ACTN3基因多态性与有氧耐力关联研究
Associations between ACTN3 Genotype and Aerobic Endurance in Northern Han Nationality Chinese
文献类型:期刊文献
中文题名:中国北方汉族人群ACTN3基因多态性与有氧耐力关联研究
英文题名:Associations between ACTN3 Genotype and Aerobic Endurance in Northern Han Nationality Chinese
作者:鲁政[1];胡扬[2]
第一作者:鲁政
机构:[1]北京联合大学应用文理学院生物学系;[2]北京体育大学
第一机构:北京联合大学应用文理学院
年份:2009
期号:2
起止页码:147-149
中文期刊名:中国运动医学杂志
外文期刊名:Chinese Journal of Sports Medicine
收录:CSTPCD;;北大核心:【北大核心2008】;CSCD:【CSCD_E2011_2012】;
基金:国家自然科学基金资助项目(30470834/C030314)
语种:中文
中文关键词:α-辅肌动蛋白-3;ACTN3;R577X基因型;有氧运动能力
外文关键词:α-actinins-3,ACTN3 R577X genotypes,aerobic ability
摘要:目的:探讨α-辅肌动蛋白-3(ACTN3)基因多态性与有氧耐力的关联性。方法:采用聚合酶链反应-限制性片段长度多态性分析(PCR-RFLP)对123名中国北方汉族优秀长跑运动员(运动员组)与206名中国北方汉族普通大学生(对照组)的ACTN3基因的R577X单核苷酸多态位点进行多态分析和比较。结果:R577X位点的分布频率在运动员组与对照组之间无显著性差异。结论:中国北方汉族人群ACTN3基因R577X位点与有氧耐力不相关。
To explore the relationship between α-actinins-3 (ACTN3) genotype and aerobic endurance in northern Han nationality Chinese, the authors compared ACTN3 R577X genotype of 123 northern Han elite long-distance running athletes with that of 206 normal northern university students through polymerase chain reaction and restriction fragment-length polymorphism (PCR-RFLP). It was found that there was no significant difference in the distribution of R577X location between northern elite long-distance running athletes and controls. It was concluded that R577X location of Han people was not correlated with aerobic endurance capacity.
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