文献类型：期刊文献

中文题名：Diversity and bioactivity of cultured aquatic fungi from the High Arctic region

英文题名：Diversity and bioactivity of cultured aquatic fungi from the High Arctic region

作者：ZHANG Tao[1];ZHAO Lili[1];YU Caiyun[2];WEI Tao[2];YU Liyan[1]

第一作者：ZHANG Tao

机构：[1]China Pharmaceutical Culture Collection,Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciences& Peking Union Medical College;[2]Beijing Key Laboratory of Bioactive Substances and Function Food,Beijing Union University

第一机构：China Pharmaceutical Culture Collection,Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciences& Peking Union Medical College

年份：2017

卷号：28

期号：1

起止页码：29-42

中文期刊名：极地科学进展：英文版

收录：CSTPCD

基金：supported by the National Natural Science Foundation of China (NSFC) (Grant nos.31670025 and 31300115);Projects of the Chinese Arctic and Antarctic Administration,State Oceanic Administration (Grant no.2013YR06006);the National Infrastructure of Microbial Resources (Grant no.NIMR-2017-3);the CAMS Innovation Fund for Medical Sciences (Grant no.2016-I2M-2-002)

语种：英文

中文关键词：生物活性分子;真菌菌株;水生环境;多样性;高海拔地区;北极;α-葡萄糖苷酶;分离培养

外文关键词：aquatic habitats, bioactivity, diversity, environmental mycology, High Arctic

摘要：This study assessed the diversity and α-glycosidase inhibitory activity of cultured fungi isolated from four aquatic environments(stream, pond, glacial ice, and estuary) in the Ny-?lesund region(Svalbard, Norway, High Arctic). A total of 134 fungal isolates were obtained from 13 water samples. Based on morphological characteristics and sequence analyses of the nuclear ribosomal DNA internal transcribed spacer region, these fungal isolates were identified as belonging to 47 species, with 26 belonging to the Ascomycota, 20 to the Basidiomycota, and one to the Zygomycota. The most frequently detected fungal species were Vishniacozyma sp. 2, Cadophora sp. 2, Phenoliferia sp. 1, Dioszegia sp. 2, and Mortierella sp.; these species occurred in 10, eight, seven, six, and five of the samples, respectively. Among the 134 fungal isolates, 17 isolates of 15 species displayed high α-glycosidase inhibitory activity in culture. The results suggest that diverse and distinct populations of cultured fungi are present in Arctic aquatic environments, and they include taxa that are potential sources of bioactive molecules that may be used as prototype drugs for medicinal proposals.
This study assessed the diversity and α-glycosidase inhibitory activity of cultured fungi isolated from four aquatic environments （stream, pond, glacial ice, and estuary） in the Ny-A.lesund region （Svalbard, Norway, High Arctic）. A total of 134 fungal isolates were obtained from 13 water samples. Based on morphological characteristics and sequence analyses of the nuclear ribosomal DNA internal transcribed spacer region, these fungal isolates were identified as belonging to 47 species, with 26 belonging to the Ascomycota, 20 to the Basidiomycota, and one to the Zygomycota. The most frequently detected fungal species were Vishniacozyma sp. 2, Cadophora sp. 2, Phenoliferia sp. 1, Dioszegia sp. 2, and Mortierella sp.; these species occurred in 10, eight, seven, six, and five of the samples, respectively. Among the 134 fungal isolates, 17 isolates of 15 species displayed high α-glycosidase inhibitory activity in culture. The results suggest that diverse and distinct populations of cultured fungi are present in Arctic aquatic environments, and they include taxa that are potential sources of bioactive molecules that may be used as prototype drugs for medicinal proposals.