文献类型：期刊文献

英文题名：Determination of Progestin Residues in Fish by UPLC-Q-TOF/MS Coupled with QuEChERS

作者：Chunxiu Gu[1]; Yanling Cheng[1]; Xin Zhen[1]; Xiaoxuan Chen[1]; Kaowen Zhou[1]

第一作者：谷春秀

机构：[1] Biochem. Eng. Coll., Beijing Union Univ., Beijing, China

第一机构：北京联合大学生物化学工程学院

年份：0

卷号：2019

起止页码：6426958 (6 pp.)-6426958 (6 pp.)

外文期刊名：Journal of Analytical Methods in Chemistry

收录：EI(收录号：19131530)

语种：英文

外文关键词：agricultural products - aquaculture - chromatography - food products - food safety - laboratory techniques - mass spectra - organic compounds - statistical analysis

摘要：A novel method was developed for simultaneous determination of 10 progestin residues in fish by ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF/MS) combined with a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) method. The homogenized samples were dispersed by water, extracted with acetonitrile, and then purified by QuEChERS reagent. The concentrated analytes were detected by UPLC-Q-TOF/MS. High linearities (R2 > 0.995) and recoveries (85.71-117.08%) at three spiked levels (5, 10, and 20 ng/g) and low relative standard deviation values (< 8.83%, n = 7) and limits of detection (0.23-0.66 ng/g) were obtained. This method is simple, rapid, reliable, sensitive, and efficient and can be used for monitoring of progestin residues in fish. This method provides a strong guarantee to deal with food emergencies for the laboratory, provides technical support for the screening and quantitative detection of progesterone in fish, and provides technical support for the food safety of aquatic products.