文献类型：期刊文献

英文题名：Excessive sleep increased the risk of incidence of cognitive impairment among older Chinese adults: a cohort study based on the Chinese Longitudinal Healthy Longevity Survey (CLHLS)

作者：Zhang, Ming[1,2,3,6];Lv, Xiaozhen[1,2];Chen, Yulu[4];Tu, Lihui[1,2];Fan, Zili[1,2];Yao, Yao[5];Yu, Xin[1,2];Guan, Nianhong[3,6];Wang, Huali[1,2]

第一作者：Zhang, Ming

通讯作者：Wang, HL[1];Guan, NH[2]

机构：[1]Peking Univ, Inst Mental Hlth, Hosp 6, Dementia Care & Res Ctr,Clin Res Div, 51 Huayuanbei Rd, Beijing 100191, Peoples R China;[2]Peking Univ, NHC Key Lab Mental Hlth, Natl Clin Res Ctr Mental Disorders, Beijing Dementia Key Lab, 51 Huayuanbei Rd, Beijing 100191, Peoples R China;[3]Sun Yat Sen Univ, Affiliated Hosp 3, Dept Psychiat, 600 Tianhe Rd, Guangzhou 510630, Peoples R China;[4]Beijing Union Univ, Teachers Coll, Dept Psychol, 5 Waiguan Xie St, Beijing 100011, Peoples R China;[5]Peking Univ, Ctr Hlth Aging & Dev Studies, Natl Sch Dev, 5 Yiheyuan Rd, Beijing 100871, Peoples R China;[6]Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou 510630, Peoples R China

第一机构：Peking Univ, Inst Mental Hlth, Hosp 6, Dementia Care & Res Ctr,Clin Res Div, 51 Huayuanbei Rd, Beijing 100191, Peoples R China

通讯机构：[1]corresponding author), Peking Univ, Inst Mental Hlth, Beijing 100191, Peoples R China;[2]corresponding author), Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou 510630, Peoples R China.

年份：2022

卷号：34

期号：8

起止页码：725-734

外文期刊名：INTERNATIONAL PSYCHOGERIATRICS

收录：;Scopus(收录号：2-s2.0-85101997229);WOS:【SSCI(收录号:WOS:000768589300001)，SCI-EXPANDED(收录号:WOS:000768589300001)】；

基金：This work was funded by the National Natural Science Foundation of China (Nos. 71490732, 82003539, 81903392, 81941021), the National Key R&D Program of China (2017YFC1311100), Capital's Funds for Health Improvement and Research (CFH2020-3-4114), Beijing Social Science Foundation (No.16JYC023), and Science and Technology Planning Project of Guangdong Province (No. 2017A070713010).

语种：英文

外文关键词：cognitive impairment; sleep duration; cohort; Chinese

摘要：Study objectives: Based on a cohort from the Chinese Longitudinal Healthy Longevity Survey (CLHLS), we aimed to evaluate the relationship between sleep duration and the incidence of cognitive impairment among older Chinese adults. Methods: We conducted a prospective analysis based on 3692 participants from the CLHLS at baseline (in 2011), and as a 3-year follow-up (till 2014), 531 participants (14.4%) had cognitive impairment, which was defined as a Mini-Mental State Examination score <24. Sleep duration was classified into three groups: short (<= 5 hours/day), normal (>5 but <10 hours), and long (>= 10 hours/day). A logistic regression model was used to examine the association between baseline sleep duration and cognitive impairment after adjusting for sociodemographic data, living habits, and health conditions. Results: Five hundred sixty-two participants (15.2%) were in the short-duration group, and 608 participants (16.5%) were in the long-duration group. After adjusting for multiple potential confounders, compared with normal sleep duration, long sleep duration was associated with the incidence of cognitive impairment (OR = 1.309, 95% CI: 1.019-1.683), especially among men (OR = 1.527, 95% CI: 1.041-2.240) and those having a primary and above education level (OR = 1.559, 95% CI: 1.029-2.361). No significant association was observed between short sleep duration and cognitive impairment (OR = 0.860, 95% CI: 0.646-1.145). Conclusions: Excessive sleep may increase the risk of cognitive impairment in older individuals. It may be a suggestive sign of early neurodegeneration and may be a useful clinical tool to identify those at a higher risk of progressing to cognitive impairment.