文献类型：期刊文献

英文题名：Preparation, structure characterization, and specific gut microbiota properties related to anti-hyperlipidemic action of type 3 resistant starch from Canna edulis

作者：Zhang, Chi[1,2,3];Qiu, Minyi[1,4];Wang, Ting[2];Luo, Linglong[1];Xu, Wenjuan[1];Wu, Jiahui[1];Zhao, Fangyuan[1];Liu, Kaiyang[1];Zhang, Yuan[3];Wang, Xueyong[1,2]

第一作者：Zhang, Chi

通讯作者：Wang, XY[1];Zhang, YA[2]

机构：[1]Beijing Univ Chinese Med, Sch Chinese Mat Med, 11 North 3rd Ring East Rd, Beijing 100029, Peoples R China;[2]Beijing Univ Chinese Med, Beijing Res Inst Chinese Med, Beijing 100029, Peoples R China;[3]Beijing Union Univ, Coll Biochem Engn, 18 Fatou Xili Dist, Beijing 100023, Peoples R China;[4]Peking Univ, Peoples Hosp, Pharm Dept, 11 Xizhimen St, Beijing 100044, Peoples R China

第一机构：Beijing Univ Chinese Med, Sch Chinese Mat Med, 11 North 3rd Ring East Rd, Beijing 100029, Peoples R China

通讯机构：[1]corresponding author), Beijing Univ Chinese Med, Sch Chinese Mat Med, 11 North 3rd Ring East Rd, Beijing 100029, Peoples R China;[2]corresponding author), Beijing Union Univ, Coll Biochem Engn, 18 Fatou Xili Dist, Beijing 100023, Peoples R China.|[1141726]北京联合大学生物化学工程学院;[11417]北京联合大学;

年份：2021

卷号：351

外文期刊名：FOOD CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000630877400001)】；

基金：This work was supported by the Beijing Municipal Natural Science Foundation (No.7192120); the National Science & Technology Fundamental Resources Investigation Program of China (No.2018FY100700); and the Science & Technology Support Plan of Guizhou Province (No.20172546, No.20204Y074).

语种：英文

外文关键词：Type 3 resistant starch; Canna edulis; Structural properties; Anti-hyperglycemia; Gut microbiota; Prebiotic

摘要：Type 3 resistant starch (RS3) was developed from Canna edulis (Ce) native starch (NS) through dual enzymatic hydrolysis and recrystallization. Thereafter, the processed Ce-RS3 was subjected to systematic characterizations for its structural properties, anti-hyperlipidemic effect, and in vivo gut microbiota modulatory function. The Ce-RS3 content was increased to 49.11% after processing under optimal conditions. Compared with NS, Ce-RS3 maintained its B-type crystallization without introducing new chemical groups. Meanwhile, it displayed coarse surfaces, higher crystallinity, more ordered structures, and a higher proportion of chains with degree of polymerization (DP) 37-100. Ce-RS3 intervention significantly alleviated dyslipidemia in hyperlipidemic mice, which was associated with increased gut microbial diversity and unique microbial enrichment, potentially mediated by its fine structure. These observations are valuable for developing RS3 from C. edulis for prebiotics applications and support the potential strategy that utilizes well-designed RS to modulate specific bacterial populations to improve health.