文献类型：期刊文献

英文题名：Study on hemodynamics in patient-specific thoracic aortic aneurysm

作者：Qiao, Ai-Ke[1];Fu, Wen-Yu[2,3];Liu, You-Jun[1]

第一作者：Qiao, Ai-Ke

通讯作者：Qiao, AK[1]

机构：[1]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China;[2]Beijing Union Univ, Coll Mech & Elect Engn, Beijing 100124, Peoples R China;[3]Beijing Univ Technol, Coll Mech Engn & Appl Elect Technol, Beijing 100101, Peoples R China

第一机构：Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China

通讯机构：[1]corresponding author), Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China.

年份：2011

卷号：1

期号：1

外文期刊名：THEORETICAL AND APPLIED MECHANICS LETTERS

收录：WOS:【ESCI(收录号:WOS:000437257800019)】；

基金：We would like to thank Dr. Makoto Ohta of Institute of Fluid Science in Tohoku University for providing us with the patient CT data. The work was supported by the National Natural Science Foundation of China (Grant Nos. 10972016 and 10872013) and Natural Science Foundation of Beijing (Grant Nos. 3092004 and 3092005).

语种：英文

外文关键词：thoracic aneurysm; CT image; CFD model; wall shear stress; hemodynamics

摘要：The objective of this study is to investigate the hemodynamics in patient-specific thoracic aortic aneurysm and discuss the reason for formation of aortic plaque. A 3-Dimensional pulsatile blood flow in thoracic aorta with a fusiform aneurysm and 3 main branched vessels was studied numerically with the average Reynolds number of 1399 and the Womersley number of 19.2. Based on the clinical 2-Dimensional CT slice data, the patient-specific geometry model was constructed using medical image process software. Unsteady, incompressible, 3-Dimensional Navier-Stokes equations were employed to solve the flow field. The temporal distributions of hemodynamic variables during the cardiac cycle such as streamlines, wall shear stresses in the arteries and aneurysm were analyzed. Growth and rupture mechanisms of thoracic aortic aneurysm in the patient can be analyzed based on patient-specific model and hemodynamics simulation. (C) 2011 The Chinese Society of Theoretical and Applied Mechanics.