文献类型：期刊文献

中文题名：肉苁蓉对大鼠抗运动性疲劳能力及脑自由基的影响

英文题名：Effects of HERBA CISTANCHES on the Ability of Resistance Exercise-induced Fatigue in Rats and Free Radical in Brain Tissue

作者：高占友[1];周海涛[2];林强[2]

第一作者：高占友

机构：[1]天津中瑞药业有限公司;[2]北京联合大学生物化学工程学院

第一机构：天津中瑞药业有限公司,天津301712

年份：2011

卷号：39

期号：16

起止页码：9592-9593

中文期刊名：安徽农业科学

外文期刊名：Journal of Anhui Agricultural Sciences

收录：北大核心:【北大核心2008】；

语种：中文

中文关键词：肉苁蓉;抗疲劳;脑自由基

外文关键词：HERBA CISTANCHES; Anti-fatigue; Free radical in brain tissue

摘要：[目的]研究肉苁蓉对大鼠抗运动性疲劳能力及脑自由基的影响,为其抗运动性疲劳功效的应用提供理论依据。[方法]适应饲养4 d后,将大鼠随机分为4组(n=15):静止灌服水组(C组)、静止灌服肉苁蓉组(M组)、运动灌服水组(T组)、运动灌服肉苁蓉组(TM组)。训练28 d后,测定各组大鼠体重、力竭游泳时间及脑组织线粒体中MDA、SOD、GSH-Px含量,观察肉苁蓉对运动大鼠抗疲劳能力及脑自由基的影响。[结果]M组、C组大鼠体重间无显著差异,T组大鼠体重小于C组大鼠(P<0.01),TM组大鼠体重小于M组大鼠(P<0.05);TM组力竭游泳时间长于T组(P<0.01);TM组MDA含量明显低于T组(P<0.01),SOD、GSH-Px活性明显高于T组(P<0.01)。[结论]肉苁蓉能延缓大鼠运动性疲劳的产生并抑制大强度力竭运动造成的大鼠脑组织脂质过氧化的程度和线粒体氧化损伤。
[Objective]To discuss the effects of HERBA CISTANCHES on the ability of resistance exercise-induced fatigue in rats and free radical in its brain tissue,so as to provide theoretical basis for the application of its resistance exercise-induced fatigue.[Method]After raised for four days,the rats were subdivided into four groups randomly（n=15） like static gavaged water group（C group）,static gavaged HERBA CISTANCHES group（M group）,movement gavaged water group（T group） and movement HERBA CISTANCHES group（TM group）.Twenty-eight days later,the body weight of rats,swimming time when they were exhausted and the content of MDA、SOD、GSH-Px in rats＇brain mitochondria in each group were determined.[Result] The rats in M group and C group had no significant differences in body weight,while those in T group were less than those in C group（P0.01）.The body weight of rats in TM group were less than those in M group（P0.05）.Rats in TM group was longer in exhaustive swimming time than T group（P0.01）.Rats in TM group was lower in MDA content（P0.01） and was higher in SOD and GSH-Px activity compared with those in T group（P0.01）.[Conclusion] HERBA CISTANCHES is provided with effect of lessening the lipid peroxidation in brain tissue of rats and oxidative damage of mitochondrial by exercise-induced fatigue.