文献类型：期刊文献

英文题名：The enrichment of chlorogenic acid from Eucommia ulmoides leaves extract by mesoporous carbons

作者：Qin, Guotong[1];Ma, Jing[1];Wei, Wei[2];Li, Jaja[2];Yue, Fangqing[2]

第一作者：Qin, Guotong

通讯作者：Wei, W[1]

机构：[1]Beihang Univ, Sch Space & Environm, 37 Xueyuan Rd, Beijing 100191, Peoples R China;[2]Beijing Union Univ, Coll Biochem Engn, 18 Sanqu, Beijing 100023, Peoples R China

第一机构：Beihang Univ, Sch Space & Environm, 37 Xueyuan Rd, Beijing 100191, Peoples R China

通讯机构：[1]corresponding author), Beijing Union Univ, Coll Biochem Engn, 18 Sanqu, Beijing 100023, Peoples R China.|[1141726]北京联合大学生物化学工程学院;[11417]北京联合大学;

年份：2018

卷号：1087

起止页码：6-13

外文期刊名：JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000432761400002)】；

基金：This work was supported by the National Science Foundation of China (Grant No 51172027 and 51272104).

语种：英文

外文关键词：Mesoporous carbon; Adsorption; Enrichment; Chlorogenic acid; Eucommia ulmoides leaves

摘要：Herein, we report an efficient separation and enrichment method for chlorogenic acid from crude extracts of Eucommia ulmoides leaves using carbon adsorbents. The effects of the pore structure of the carbon adsorbents on the adsorption capacity were studied. Of the four adsorbents investigated, mesoporous carbon (MC3) showed the highest adsorption capacity (294 mg/g of carbon) for chlorogenic acid due to its high mesopore volume. The static adsorption of CGA on carbon can be accurately described using the Freundlich equation. The kinetics of adsorption follow a pseudo-second-order process. External mass transfer was the controlling step of the adsorption process. Dynamic adsorption on MC3 demonstrated that chlorogenic acid began to break through after 28 bed volumes of extract was loaded. This mesoporous carbon-treatment procedure is safe, economic and has the potential to be scaled up for commercial application.