文献类型：期刊文献

英文题名：Excessive sleep increased the risk of incidence of cognitive impairment among older Chinese adults: A cohort study based on the Chinese Longitudinal Healthy Longevity Survey (CLHLS)

作者：Zhang M.; Lv X.; Chen Y.; Tu L.; Fan Z.; Yao Y.; Yu X.; Guan N.; Wang H.

机构：[1]Dementia Care and Research Center, Clinical Research Division, Peking University Institute of Mental Health (Sixth Hospital), No. 51 Huayuanbei Road, Haidian District, Beijing, 100191, China;[2]Beijing Dementia Key Lab, National Clinical Research Center for Mental Disorders, Nhc Key Laboratory of Mental Health (Peking University), No. 51 Huayuanbei Road, Haidian District, Beijing, 100191, China;[3]Department of Psychiatry, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Tianhe District, Guangzhou, 510630, China;[4]Department of Psychology, Teachers' College, Beijing Union University, No. 5 Waiguan Xie Street, , Beijing, Chaoyang District, 100011, China;[5]Center for Healthy Aging and Development Studies, National School of Development, Peking University, No.5 Yiheyuan Road, Haidian District, Beijing, 100871, China

第一机构：Dementia Care and Research Center, Clinical Research Division, Peking University Institute of Mental Health (Sixth Hospital), No. 51 Huayuanbei Road, Haidian District, Beijing, 100191, China

年份：2022

卷号：34

期号：8

起止页码：725-734

外文期刊名：International Psychogeriatrics

收录：Scopus(收录号：2-s2.0-85101997229)

语种：英文

外文关键词：Chinese; cognitive impairment; cohort; sleep duration

摘要：Study objectives: Based on a cohort from the Chinese Longitudinal Healthy Longevity Survey (CLHLS), we aimed to evaluate the relationship between sleep duration and the incidence of cognitive impairment among older Chinese adults. Methods: We conducted a prospective analysis based on 3692 participants from the CLHLS at baseline (in 2011), and as a 3-year follow-up (till 2014), 531 participants (14.4%) had cognitive impairment, which was defined as a Mini-Mental State Examination score <24. Sleep duration was classified into three groups: short (≤5 hours/day), normal (>5 but <10 hours), and long (≥10 hours/day). A logistic regression model was used to examine the association between baseline sleep duration and cognitive impairment after adjusting for sociodemographic data, living habits, and health conditions. Results: Five hundred sixty-two participants (15.2%) were in the short-duration group, and 608 participants (16.5%) were in the long-duration group. After adjusting for multiple potential confounders, compared with normal sleep duration, long sleep duration was associated with the incidence of cognitive impairment (OR = 1.309, 95% CI: 1.019-1.683), especially among men (OR = 1.527, 95% CI: 1.041-2.240) and those having a primary and above education level (OR = 1.559, 95% CI: 1.029-2.361). No significant association was observed between short sleep duration and cognitive impairment (OR = 0.860, 95% CI: 0.646-1.145). Conclusions: Excessive sleep may increase the risk of cognitive impairment in older individuals. It may be a suggestive sign of early neurodegeneration and may be a useful clinical tool to identify those at a higher risk of progressing to cognitive impairment. ?