文献类型：期刊文献

中文题名：Fermented soy whey induced changes on intestinal microbiota and metabolic in?uence in mice

作者：Wei Han[1];Xuhui Zhuang[1];Qian Liu[2];Bo Sun[1];Haijiang Miao[1];Xiaolin Zhang[3]

第一作者：Wei Han

机构：[1]Academy of State Administration of Grain,Beijing 100037,China;[2]Beijing Key Laboratory of Bioactive Substances and Functional Foods,Beijing Union University,Beijing 100191,China;[3]COFCO Nutrition and Health Institute,Beijing 102209,China

第一机构：Academy of State Administration of Grain,Beijing 100037,China

年份：2022

卷号：11

期号：1

起止页码：41-48

中文期刊名：食品科学与人类健康（英文）

外文期刊名：Food Science and Human Wellness

收录：Scopus

语种：英文

中文关键词：Soy whey;Microbiota;Short chain fatty acids;Lactobacillus casei;Akkermansia muciniphila

摘要：Soy whey(SW)is generated as process waste while preparing soy protein isolates(SPI),and causing severe environmental pollution.Therefore,its value-added utilization is of prime importance for transforming and upgrading traditional industry.This study aims to utilize SW as a substrate for the growth of probiotics and produce a SW based synbiotics.By a series of trials,the effect of the dietary supplementation with this fermented SW(FSW)was analyzed on ICR mice's body weight,metabolites,and intestinal microbiota in 4 weeks.The results showed that,when SW was concentrated 15 times,the count of viable Lactobacillus casei reached 3.4×10^(9) CFU/mL by liquid fermentation method,which was the highest viable cell count among all test strains.In this FSW,the protein,amino acid,total dietary fibre,soluble dietary fibre,and oligosaccharide were 2.10%,1.63%,0.52%,0.51% and 0.79%,respectively.Compared to two control group,the total yields of the short chain fatty acids(SCFAs)were significantly improved(75%-125% at average),while the SCFAs structure was also significantly changed(especially acetic acid and butyrate)in the faeces of mice fed FSW.Meanwhile,FSW dietary addition was associated with the diversity and richness of the intestinal microbiota.Obviously,with mice's body weight loss,Firmicutes/Bacteroides ratio reduced accordingly(<1.21),and the abundance of Akkermansia muciniphila was significantly increased(the maximum amount was about 0.013%).In summary,our results indicated that the dietary supplementation of FSW affected mice's intestinal microbiota and metabolism and improved their health profile.