文献类型：期刊文献

英文题名：Determination of Progestin Residues in Fish by UPLC-Q-TOF/MS Coupled with QuEChERS

作者：Gu, Chunxiu[1,2];Cheng, Yanling[1,2];Zhen, Xin[1];Chen, Xiaoxuan[1];Zhou, Kaowen[1,2]

第一作者：谷春秀;Gu, Chunxiu

通讯作者：Zhou, KW[1];Zhou, KW[2]

机构：[1]Beijing Union Univ, Biochem Engn Coll, Beijing 100023, Peoples R China;[2]Beijing Key Lab Biomass Waste Resource Utilizat, Beijing 100023, Peoples R China

第一机构：北京联合大学生物化学工程学院

通讯机构：[1]corresponding author), Beijing Union Univ, Biochem Engn Coll, Beijing 100023, Peoples R China;[2]corresponding author), Beijing Key Lab Biomass Waste Resource Utilizat, Beijing 100023, Peoples R China.|[1141726]北京联合大学生物化学工程学院;[11417]北京联合大学;

年份：2019

卷号：2019

外文期刊名：JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY

收录：;Scopus(收录号：2-s2.0-85066075990);WOS:【SCI-EXPANDED(收录号:WOS:000473581500001)】；

基金：is work was supported by the Beijing Natural Science Foundation (2152013), State 863 Program (2015AA020200), and College Students' Scientific and Technological Innovation Project (201811417SJ109 and 201811417XJ170).

语种：英文

摘要：A novel method was developed for simultaneous determination of 10 progestin residues in fish by ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF/MS) combined with a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) method. The homogenized samples were dispersed by water, extracted with acetonitrile, and then purified by QuEChERS reagent. The concentrated analytes were detected by UPLC-Q-TOF/MS. High linearities (R-2>0.995) and recoveries (85.71-117.08%) at three spiked levels (5, 10, and 20ng/g) and low relative standard deviation values (<8.83%, n=7) and limits of detection (0.23-0.66ng/g) were obtained. This method is simple, rapid, reliable, sensitive, and efficient and can be used for monitoring of progestin residues in fish. This method provides a strong guarantee to deal with food emergencies for the laboratory, provides technical support for the screening and quantitative detection of progesterone in fish, and provides technical support for the food safety of aquatic products.